What Africa can do to accelerate and sustain progress against malaria (Publications)
After a longstanding global presence, malaria is now largely non-existent or suppressed in most parts of the world. Today, cases and deaths are primarily concentrated in sub-Saharan Africa. According
Model-informed target product profiles of long-acting-injectables for use as seasonal malaria prevention (Publications)
Seasonal malaria chemoprevention (SMC) has proven highly efficacious in reducing malaria incidence. However, the continued success of SMC is threatened by the spread of resistance against one of its m
Investigation of the effect of structure modification of furamidine on the DNA minor groove binding and antiprotozoal activity (Publications)
New analogs of the antiprotozoal agent Furamidine were prepared utilizing Stille coupling reactions and amidation of the bisnitrile intermediate using lithium bis-trimethylsilylamide. Both the phenyl
Effect of residential relocation on environmental exposures in European cohorts: an exposome-wide approach (Publications)
Residential relocation is increasingly used as a natural experiment in epidemiological studies to assess the health impact of changes in environmental exposures. Since the likelihood of relocation can
Heat-related cardiorespiratory mortality: effect modification by air pollution across 482 cities from 24 countries (Publications)
Background Evidence on the potential interactive effects of heat and ambient air pollution on cause-specific mortality is inconclusive and limited to selected locations. Objectives We investigated the
ePOCT+ and the medAL-<em>suite</em>: development of an electronic clinical decision support algorithm and digital platform for pediatric outpatients... (Publications)
Electronic clinical decision support algorithms (CDSAs) have been developed to address high childhood mortality and inappropriate antibiotic prescription by helping clinicians adhere to guidelines. Pr
Health worker compliance with severe malaria treatment guidelines in the context of implementing pre-referral rectal artesunate in the Democratic... (Publications)
BACKGROUND: For a full treatment course of severe malaria, community-administered pre-referral rectal artesunate (RAS) should be completed by post-referral treatment consisting of an injectable antima
Associations between exposure to blue spaces and natural and cause-specific mortality in Greece: an ecological study (Publications)
BACKGROUND: A growing body of evidence suggests that exposure to natural environments, such as green space, may have a beneficial role in health. However, there is limited evidence regarding the effec
Ivermectin and moxidectin against soil-transmitted helminth infections (Publications)
Ivermectin and moxidectin, two macrocyclic lactones, are potent antiparasitic drugs currently registered and mainly used against filarial diseases; however, their potential value for improved soil-tra