Comparison of <em>Plasmodium falciparum</em> allelic frequency distribution in different endemic settings by high-resolution genotyping (Publications)
BACKGROUND: The diversity of genotyping markers of Plasmodium falciparum depends on transmission intensity. It has been reported that the diversity of the merozoite surface protein 2 (msp2) is greater
Simulation of the cost-effectiveness of malaria vaccines (Publications)
BACKGROUND: A wide range of possible malaria vaccines is being considered and there is a need to identify which vaccines should be prioritized for clinical development. An important element of the inf
Identification of compounds with anti-proliferative activity against <em>Trypanosoma brucei brucei</em> strain 427 by a whole cell viability based HTS... (Publications)
Human African Trypanosomiasis (HAT) is caused by two trypanosome sub-species, Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense. Drugs available for the treatment of HAT have significant
<em>Anopheles plumbeus</em> (Diptera: Culicidae) in Europe: a mere nuisance mosquito or potential malaria vector? (Publications)
ABSTRACT: BACKGROUND: Anopheles plumbeus has been recognized as a minor vector for human malaria in Europe since the beginning of the 20th century. In recent years this tree hole breeding mosquito spe
Laboratory and field trials at Ifakara (Kilombero District, Tanzania) on the plant molluscicide <em>Swartzia madagascariensis</em> (Publications)
The molluscicidal activity of crushed seed pods of Swartzia madagascariensis was assessed by laboratory and field trials. Mature dry seed pods were ground and extracted in tap water for 24 h. Water ex
Improved protective efficacy of a species-specific DNA vaccine encoding mycolyl-transferase Ag85A from <em>Mycobacterium ulcerans</em> by homologous... (Publications)
Vaccination with plasmid DNA encoding Ag85A from M. bovis BCG can partially protect C57BL/6 mice against a subsequent footpad challenge with M. ulcerans. Unfortunately, this cross-reactive protection
Molecular characterization of <em>Mycobacterium bovis</em> strains isolated from cattle slaughtered at two abattoirs in Algeria (Publications)
BACKGROUND: Bovine Tuberculosis is prevalent in Algeria despite governmental attempts to control the disease. The objective of this study was to conduct, for the first time, molecular characterization
Rapid and accurate detection of <em>Mycobacterium tuberculosis</em> in sputum samples by Cepheid Xpert MTB/RIF assay - a clinical validation study (Publications)
BACKGROUND: A crucial impediment to global tuberculosis control is the lack of an accurate, rapid diagnostic test for detection of patients with active TB. A new, rapid diagnostic method, (Cepheid) Xp