Modelling lymphatic filariasis transmission and control: modelling frameworks, lessons learned and future directions (Publications)
Mathematical modelling provides a useful tool for policy making and planning in lymphatic filariasis control programmes, by providing trend forecasts based on sound scientific knowledge and principles
Assessing numbers and faces: a prerequisite for improving access to lymphatic filariasis morbidity care (Publications)
Concerted efforts to eliminate lymphatic filariasis worldwide have registered success; multiple rounds of mass drug administration have led to the interruption of transmission in many previously endem
Clinical features for diagnosis of pneumonia in children younger than 5 years: a systematic review and meta-analysis (Publications)
BACKGROUND: Pneumonia is the biggest cause of deaths in young children in developing countries, but early diagnosis and intervention can effectively reduce mortality. We aimed to assess the diagnostic
Detection of <em>Mycobacterium tuberculosis</em> by EasyNAT diagnostic kit in sputum samples from Tanzania (Publications)
EasyNAT was evaluated for detection of tuberculosis in sputum smears of presumptive pulmonary TB patients in an African high TB and HIV setting. The sensitivity of EasyNAT was 66.7%, specificity and p
Impact de l'urbanisation sur l'indice plasmodique et les densités parasitaires chez les enfants de 0 à 5 ans dans la commune de Yopougon, Abidjan... (Publications)
From September 23-30, 2005, we conducted a cross-sectional study in six townships of Yopougon, a municipality of Abidjan. These townships were grouped in three levels of urbanization (village, precari
Inhibitors of plasmodial serine hydroxymethyltransferase (SHMT): cocrystal structures of pyrazolopyrans with potent blood- and liver-stage activities (Publications)
Several of the enzymes related to the folate cycle are well-known for their role as clinically validated antimalarial targets. Nevertheless for serine hydroxymethyltransferase (SHMT), one of the key e
Discovery and optimisation studies of antimalarial phenotypic hits (Publications)
There is an urgent need for the development of new antimalarial compounds. As a result of a phenotypic screen, several compounds with potent activity against the parasite Plasmodium falciparum were id
Outcomes mapping study for childhood vaccination communication: too few concepts were measured in too many ways (Publications)
OBJECTIVES: The objectives of this paper are: 1) to comprehensively catalogue outcomes measured in trials of childhood vaccination communication interventions; and 2) to analyse patterns and trends in