Optimization and validation of multi-coloured capillary electrophoresis for genotyping of <em>Plasmodium falciparum</em> merozoite surface proteins... (Publications)
BACKGROUND: Genotyping of Plasmodium falciparum based on PCR amplification of the polymorphic genes encoding the merozoite surface proteins 1 and 2 (msp1 and msp2) is well established in the field of
Patterns and risk factors of helminthiasis and anemia in a rural and a peri-urban community in Zanzibar, in the context of helminth control programs (Publications)
BACKGROUND: The control of helminth infections and prevention of anemia in developing countries are of considerable public health importance. The purpose of this study was to determine patterns and ri
Diagnostic accuracy of Kato-Katz and FLOTAC for assessing anthelmintic drug efficacy (Publications)
BACKGROUND: Sensitive diagnostic tools are required for an accurate assessment of prevalence and intensity of helminth infections in areas undergoing regular deworming, and for monitoring anthelmintic
How much remains undetected? Probability of molecular detection of human <em>Plasmodia</em> in the field (Publications)
BACKGROUND: In malaria endemic areas, most people are simultaneously infected with different parasite clones. Detection of individual clones is hampered when their densities fluctuate around the detec
Modern geographical reconnaissance of target populations in malaria elimination zones (Publications)
ABSTRACT: BACKGROUND: Geographical Reconnaissance (GR) operations using Personal Digital Assistants (PDAs) and Global Positioning Systems (GPS) have been conducted in the elimination provinces of Temo
Routine delivery of artemisinin-based combination treatment at fixed health facilities reduces malaria prevalence in Tanzania: an observational study (Publications)
ABSTRACT: BACKGROUND: Artemisinin-based combination therapy (ACT) has been promoted as a means to reduce malaria transmission due to their ability to kill both asexual blood stages of malaria parasite
Adenosine kinase of <em>T. b. Rhodesiense</em> identified as the putative target of 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine using chemical... (Publications)
BACKGROUND: Human African trypanosomiasis (HAT), a major parasitic disease spread in Africa, urgently needs novel targets and new efficacious chemotherapeutic agents. Recently, we discovered that 4-[5
