Isothermal microcalorimetry to study the activity of triclabendazole and its metabolites on juvenile and adult <em>Fasciola hepatica</em> (Publications)
Isothermal microcalorimetry (IMC) is an analytical tool that continuously measures the heat flow generated by chemical, physical or biological processes. We have demonstrated that IMC is a useful tool
Anémie dans une école du Cambodge rural: détection, prévalence et liens avec les parasitoses intestinales et la malnutrition (Publications)
According to WHO, half of the world's children suffers from anaemia, which is a silent and neglected endemic resulting from three major causes: iron deficiency intestinal worms and malaria. A two mont
Efficacy and safety of mefloquine, artesunate, mefloquine-artesunate, and praziquantel against <em>Schistosoma haematobium</em>: randomized,... (Publications)
BACKGROUND: Morbidity control of schistosomiasis relies on a single drug, praziquantel. The antimalarial drug mefloquine possesses interesting antischistosomal properties, yet no clinical studies have
Anthelmintic activity of artesunate against <em>Fasciola hepatica</em> in naturally infected sheep (Publications)
In light of rapidly spreading triclabendazole resistance alternative fasciocidal drugs are urgently needed. Following up on promising results obtained with artemether in Fasciola hepatica infected she
Effect of irrigation and large dams on the burden of malaria on a global and regional scale (Publications)
Human-made ecologic transformations have occurred at an unprecedented rate over the past 50 years. Prominent among them are water resource development projects. An estimated 40,000 large dams and 800,
<em>Plasmodium berghei</em> ANKA: selection of resistance to piperaquine and lumefantrine in a mouse model (Publications)
We have selected piperaquine (PQ) and lumefantrine (LM) resistant Plasmodium berghei ANKA parasite lines in mice by drug pressure. Effective doses that reduce parasitaemia by 90% (ED(90)) of PQ and LM
The role of parasitic infections in atopic diseases in rural schoolchildren (Publications)
BACKGROUND: There is increasing evidence that the farming environment has a protective effect as regards allergic diseases. Exposure to animal parasites, particularly helminth infections, is common in
Update on the diagnosis and treatment of food-borne trematode infections (Publications)
PURPOSE OF REVIEW: More than 40 million people are affected by food-borne trematode infections. Diagnosis is unsatisfactory and there are only two drugs available for treatment and control: praziquant
