Antitrypanosomal activity of sesquiterpene lactones from <em>Helianthus tuberosus</em> L. including a new furanoheliangolide with an unusual structure (Publications)
As part of our efforts to exploit the antitrypanosomal potential of sesquiterpene lactones (STL) from Helianthus tuberosus L. (Asteraceae), besides the known 4,15-iso-atriplicolide tiglate, -methacryl
Safely managed hygiene: a risk-based assessment of handwashing water quality (Publications)
Sustainable Development Goal (SDG) Indicator 6.2.1 requires household handwashing facilities to have soap and water, but there are no guidelines for handwashing water quality. In contrast, drinking wa
Hemozoin-catalyzed precipitation polymerization as an assay for malaria diagnosis (Publications)
Methods to diagnose malaria are of paramount interest to eradicate the disease. Current methods have severe limitations, as they are either costly or not sensitive enough to detect low levels of paras
Antiprotozoal germacranolide sesquiterpene lactones from <em>Tanacetum sonbolii</em> (Publications)
A phytochemical investigation of extracts from flowers and aerial parts of Tanacetum sonbolii afforded 7 new germacranolide sesquiterpene lactones. The structures were established by a combination of
Maternal hepatitis B infection burden, comorbidity and pregnancy outcome in a low-income population on the Myanmar-Thailand border: a retrospective... (Publications)
Objectives. Hepatitis B virus (HBV) was believed to have minimal impact on pregnancy outcomes apart from the risk of perinatal transmission. In more recent years, there have been reports of adverse as
A qualitative study of the dissemination and diffusion of innovations: bottom up experiences of senior managers in three health districts in South... (Publications)
BACKGROUND: In 2012 the South African National Department of Health (SA NDoH) set out, using a top down process, to implement several innovations in eleven health districts in order to test reforms to
Prognostic accuracy of soluble triggering receptor expressed on myeloid cells (strem-1)-based algorithms in febrile adults presenting to Tanzanian... (Publications)
BACKGROUND: The inability to identify individuals with acute fever at risk of death is a barrier to effective triage and management of severe infections, especially in low-resource settings. Since end
Multiple introductions of <em>Mycobacterium tuberculosis</em> lineage 2-Beijing into Africa over centuries (Publications)
The Lineage 2–Beijing (L2–Beijing) sub-lineage of Mycobacterium tuberculosis has received much attention due to its high virulence, fast disease progression, and association with antibiotic resistance
Epidemiologie, Klinik, Diagnostik und Therapie von Infektionen durch <em>Mycobacterium chimaera</em> (Publications)
The recognition, correct diagnosis and adequate clinical management of infections caused by atypical mycobacteria are challenging tasks in clinical practice. Invasive infections caused by Mycobacteriu
