Nearly complete genome sequence of a novel phlebovirus-like virus detected in a human plasma sample by high-throughput sequencing (Publications)
Here, we report a novel phlebovirus-like virus sequence detected in a plasma sample from a febrile adult patient collected in the United Republic of Tanzania in 2014. A nearly complete RNA sequence wa
Short course amphotericin B in addition to sertraline and fluconazole for treatment of HIV-associated cryptococcal meningitis in rural Tanzania (Publications)
BACKGROUND: Cryptococcal meningitis accounts for 15% of all AIDS-mortality globally. Most cases in low- and middle-income countries are treated with fluconazole monotherapy, which is associated with a
Dog ecology, bite incidence, and disease awareness: a cross-sectional survey among a rabies-affected community in the Democratic Republic of the Congo (Publications)
Despite the existence of safe and efficacious human and animal rabies vaccines, millions of people remain at risk of exposure to this deadly zoonotic disease through bites of infected dogs. Sub-Sahara
Short-term associations between daily mortality and ambient particulate matter, nitrogen dioxide, and the air quality index in a Middle Eastern... (Publications)
There is limited evidence for short-term association between mortality and ambient air pollution in the Middle East and no study has evaluated exposure windows of about a month prior to death. We inve
Safety and tolerance of lymph node biopsies from chronic HIV-1 volunteers in rural Tanzania (Publications)
OBJECTIVE: HIV-1 rapidly establishes a persistent infection that can be contained under life-long antiretroviral therapy (ART) but not cured. One major viral reservoir is the peripheral lymph node (LN
Genome-wide mutational biases fuel transcriptional diversity in the <em>Mycobacterium tuberculosis</em> complex (Publications)
The Mycobacterium tuberculosis complex (MTBC) members display different host-specificities and virulence phenotypes. Here, we have performed a comprehensive RNAseq and methylome analysis of the main c
Host cytoskeleton remodeling throughout the blood stages of <em>Plasmodium falciparum</em> (Publications)
SUMMARYThe asexual intraerythrocytic development of Plasmodium falciparum, causing the most severe form of human malaria, is marked by extensive host cell remodeling. Throughout the processes of invas
Five-year impact of different multi-year mass drug administration strategies on childhood <em>Schistosoma mansoni</em>-associated morbidity: a... (Publications)
The WHO recommends mass treatment with praziquantel as the primary approach for Schistosoma mansoni-related morbidity control in endemic populations. The Schistosomiasis Consortium for Operational Res
Safety profile of the meningococcal conjugate vaccine (Menafrivac™) in clinical trials and vaccination campaigns: a review of published studies (Publications)
The study aimed to assess the capacity of AEFI surveillance during vaccination campaigns with the new conjugate meningitis vaccine (MenAfrivac). A systematic review of studies on MenAfrivac published