Incorporating operational research in programmes funded by the Global Fund to Fight AIDS, Tuberculosis and Malaria in four sub-Saharan African... (Publications)
BACKGROUND: The current study builds upon a previous situation analysis of the extent to which grants from the Global Fund to Fight AIDS, Tuberculosis and Malaria (Global Fund) are being utilized to s
Home-based oral self-testing for absent and declining individuals during a door-to-door HIV testing campaign in rural Lesotho (HOSENG): a... (Publications)
BACKGROUND: In sub-Saharan Africa, home-based HIV testing is validated and accepted, but coverage is low because household members are often absent during home-based testing campaigns. We aimed to mea
Discovery of FNDR-20123, a histone deacetylase inhibitor for the treatment of <em>Plasmodium falciparum</em> malaria (Publications)
BACKGROUND: Emergence of anti-malarial drug resistance and perpetual increase in malaria incidence necessitates the development of novel anti-malarials. Histone deacetylases (HDAC) has been shown to b
Cohort profile: molecular signature in pregnancy (MSP): longitudinal high-frequency sampling to characterise cross-omic trajectories in pregnancy in a... (Publications)
PURPOSE: A successful pregnancy relies on the interplay of various biological systems. Deviations from the norm within a system or intersystemic interactions may result in pregnancy-associated complic
Towards integrated surveillance-response systems for the prevention of future pandemics (Publications)
Most human pathogens originate from non-human hosts and certain pathogens persist in animal reservoirs. The transmission of such pathogens to humans may lead to self-sustaining chains of transmission.
Blood gene transcript signature profiling in pregnancies resulting in preterm birth: a systematic review (Publications)
Objective: To pursue a systematic review and summarise the current evidence for the potential of transcriptome molecular profiling in investigating the preterm phenotype. Study design: We systematical
Molecular epidemiology of leprosy: an update (Publications)
Molecular epidemiology investigations are notoriously challenging in the leprosy field mainly because the inherent characteristics of the disease as well as its yet uncultivated causative agents, Myco
<em>Mycobacterium tuberculosis</em> in a primagam negative wild caught captive olive baboon (<em>Papio anubis</em>) in Ethiopia (Publications)
A free-roaming wild olive baboon (Papio anubis) was caught in the compound of a hospital and kept in captivity pending reintroduction to the wild. The animal had a sporadic dry cough but was TB negati
