A new chemotype with promise against <em>Trypanosoma cruzi</em> (Publications)
Pyridyl benzamide 2 is a potent inhibitor of Trypanosoma cruzi, but not other protozoan parasites, and had a selectivity-index of > /=10. The initial structure-activity relationship (SAR) indicates th
Safety and immunogenicity of the RTS,S/AS01 malaria vaccine in infants and children identified as HIV-infected during a randomized trial in... (Publications)
BACKGROUND: We assessed the safety and immunogenicity of the RTS,S/AS01 malaria vaccine in a subset of children identified as HIV-infected during a large phase III randomized controlled trial conducte
Going operational with health systems governance: supervision and incentives to health workers for increased quality of care in Tanzania (Publications)
Improving the quality of care is increasingly recognized as a priority of health systems in low- and middle-income countries. Given the labour-intensive nature of healthcare interventions, quality of
Antenatal care and skilled delivery service utilization in Somali pastoral communities of eastern Ethiopia (Publications)
OBJECTIVE: To assess maternal health care service utilization and associated factors in Somali pastoral communities of Eastern Ethiopia. METHODS: Community-based cross-sectional study complemented by
Bayesian conditional autoregressive models to assess spatial patterns of diarrhoea risk among children under the age of 5 years in Mbour, Senegal. (Publications)
Diarrhoeal diseases remain a major public health problem, causing more than half a million child deaths every year, particularly in low- and middle-income countries (LMICs). Despite existing knowledge
Mapping routine malaria incidence at village level for targeted control in Papua New Guinea (Publications)
Malaria surveillance and response-systems are essential for identifying the areas most affected by malaria and for targeting interventions and optimising resources. This study aimed to assess whether
Atopy modifies the association between inhaled corticosteroid use and lung function decline in patients with asthma (Publications)
BACKGROUND: Inhaled corticosteroids (ICSs) are the mainstay of asthma treatment, but response to medication is variable. Patients with allergic inflammation generally show a better short-term response
Presence of <em>Borrelia</em> spp. DNA in ticks, but absence of <em>Borrelia </em>spp. and of <em>Leptospira</em> spp. DNA in blood of fever patients... (Publications)
The occurrence of tick-borne relapsing fever and leptospirosis in humans in Madagascar remains unclear despite the presence of their potential vectors and reservoir hosts. We screened 255 Amblyomma va
