Rapid microarray-based method for monitoring of all currently known single-nucleotide polymorphisms associated with parasite resistance to antimalaria... (Publications)
Parasite drug resistance is partly conferred by single-nucleotide polymorphisms (SNPs), and monitoring them has been proposed as an alternative to monitoring drug resistance. Therefore, techniques are
Molecular characterization and drug resistance testing of <em>Mycobacterium tuberculosis</em> isolates from Chad (Publications)
The molecular characterizations of the first 40 Mycobacterium tuberculosis isolates from Chad revealed a high proportion of isolates of the Cameroon family (33%), of which one isolate showed a monodru
Synthesis and biological evaluation of substrate-based inhibitors of 6-phosphogluconate dehydrogenase as potential drugs against African... (Publications)
The synthesis and biological evaluation of three series of 6-phosphogluconate (6PG) analogues is described. (2R)-2-Methyl-4,5-dideoxy, (2R)-2-methyl-4-deoxy and 2,4-dideoxy analogues of 6PG were teste
Use of the immunodominant 18-kiloDalton small heat shock protein as a serological marker for exposure to <em>Mycobacterium ulcerans</em> (Publications)
While it is well established that proximity to wetlands is a risk factor for contracting Buruli ulcer, it is not clear what proportion of a population living in an area where the etiologic agent, Myco
Deltamethrin-impregnated bednets reduce human landing rates of sandfly vector <em>Lutzomyia longipalpis</em> in Amazon households (Publications)
The entomological efficacy of using 25% deltamethrin EC insecticide-treated bednets (ITNs) was evaluated against the sandfly Lutzomyia longipalpis Lutz and Neiva (Diptera: Psychodidae), the principal
Disseminated histoplasmosis and aids: relapse and late mortality in endemic area in north-eastern Brazil (Publications)
The State of Ceara in north-eastern Brazil has one of the highest rates in the world of relapse and death due to disseminated histoplasmosis (DH) in acquired immunodeficiency syndrome (AIDS) patients.
Withholding antimalarials in febrile children who have a negative result for a rapid diagnostic test (Publications)
Background. The availability of a rapid diagnostic test for malaria (RDTm) allows accurate diagnosis at all levels of health facilities. The objective of the present study was to evaluate the safety o
