An amphiphilic graft copolymer-based nanoparticle platform for reduction-responsive anticancer and antimalarial drug delivery (Publications)
Medical applications of anticancer and antimalarial drugs often suffer from low aqueous solubility, high systemic toxicity, and metabolic instability. Smart nanocarrier-based drug delivery systems pro
Prevalence and outcomes of hepatitis B coinfection and associated liver disease among antiretroviral therapy-naive individuals in a rural Tanzanian... (Publications)
Background. We evaluated the prevalence of chronic hepatitis B virus (HBV) infection and liver fibrosis/cirrhosis in human immunodeficiency virus (HIV)-infected individuals enrolled in a rural Tanzani
Spatial mapping and prediction of <em>Plasmodium falciparum</em> infection risk among school-aged children in Côte d'Ivoire (Publications)
BACKGROUND: In Cote d'Ivoire, malaria remains a major public health issue, and thus a priority to be tackled. The aim of this study was to identify spatially explicit indicators of Plasmodium falcipar
Mapping of research on maternal health interventions in low- and middle-income countries: a review of 2292 publications between 2000 and 2012 (Publications)
BACKGROUND: Progress in achieving maternal health goals and the rates of reductions in deaths from individual conditions have varied over time and across countries. Assessing whether research prioriti
Operational challenges to continuous LLIN distribution: a qualitative rapid assessment in four countries (Publications)
BACKGROUND: The World Health Organization recommends that long-lasting insecticidal nets (LLINs) for malaria prevention should be distributed continuously through antenatal care (ANC) and the expanded
Clinical implications of <em>Mycobacterium chimaera</em> detection in thermoregulatory devices used for extracorporeal membrane oxygenation (ECMO),... (Publications)
Mycobacterium chimaera, a non-tuberculous mycobacterium, was recently identified as causative agent of deep-seated infections in patients who had previously undergone open-chest cardiac surgery. Outbr
Efficacy and safety of tribendimidine against <em>Opisthorchis viverrini</em>: two randomised, parallel-group, single-blind, dose-ranging, phase 2... (Publications)
BACKGROUND: Treatment of the liver fluke infection Opisthorchis viverrini relies exclusively on praziquantel. Tribendimidine could be an alternative treatment option. We aimed to assess the efficacy a
A worldwide map of <em>Plasmodium falciparum</em> K13-propeller polymorphisms (Publications)
BACKGROUND: Recent gains in reducing the global burden of malaria are threatened by the emergence of Plasmodium falciparum resistance to artemisinins. The discovery that mutations in portions of a P.
Sensitive and accurate quantification of human malaria parasites using droplet digital PCR (ddPCR) (Publications)
Accurate quantification of parasite density in the human host is essential for understanding the biology and pathology of malaria. Semi-quantitative molecular methods are widely applied, but the need
