Cyclombandakamines A1 and A2, oxygen-bridged naphthylisoquinoline dimers from a Congolese <em>Ancistrocladus liana</em> (Publications)
Cyclombandakamines A1 (1) and A2 (2), both with an unprecedented pyrane-cyclohexenone-dihydrofuran sequence and six stereocenters and two chiral axes, are the first oxygen-bridged dimeric naphthylisoq
Structure of the malaria vaccine candidate antigen CyRPA and its complex with a parasite invasion inhibitory antibody (Publications)
Invasion of erythrocytes by Plasmodial merozoites is a composite process involving the interplay of several proteins. Among them, the Plasmodium falciparum Cysteine-Rich Protective Antigen (PfCyRPA) i
Population pharmacokinetic modeling of tribendimidine metabolites in <em>Opisthorchis viverrini</em>-infected adults (Publications)
There is a pressing need for alternative treatments against the liver fluke Opisthorchis viverrini Oral tribendimidine is a promising candidate, but its population pharmacokinetic properties are unkno
Induction of humoral immune response to multiple recombinant <em>Rhipicephalus appendiculatus</em> antigens and their effect on tick feeding success... (Publications)
BACKGROUND: Rhipicephalus appendiculatus is the primary vector of Theileria parva, the etiological agent of East Coast fever (ECF), a devastating disease of cattle in sub-Saharan Africa. We hypothesiz
Host-directed therapies for infectious diseases: current status, recent progress, and future prospects (Publications)
Despite extensive global efforts in the fight against killer infectious diseases, they still cause one in four deaths worldwide and are important causes of long-term functional disability arising from
Varicella seroprevalence in individuals with a negative or unknown varicella history - results from a large travel clinic in Switzerland between 2008... (Publications)
QUESTION UNDER STUDY: In Switzerland, vaccination against varicella is not recommended in the basic immunisation schedule. However, for individuals aged 11-40 years who do not have a reliable varicell
Perspectives on the methods of a large systematic mapping of maternal health interventions (Publications)
BACKGROUND: Mapping studies describe a broad body of literature, and differ from classical systematic reviews, which assess more narrowly-defined questions and evaluate the quality of the studies incl
Exposure to ambient air pollution and the risk of inflammatory bowel disease: a European nested case-control study (Publications)
BACKGROUND: Industrialization has been linked to the etiology of inflammatory bowel disease (IBD). AIM: We investigated the association between air pollution exposure and IBD. METHODS: The European Pr