Tuberculosis control in refugee populations: a challenge to both relief agencies and national programs (Publications)
Today's worldwide tuberculosis epidemic and the movement of a growing number of refugees overlap geographically and have made tuberculosis control in refugee populations an issue of increasing importa
Pharmacokinetic parameters of artesunate and dihydroartemisinin in rats infected with <em>Fasciola hepatica</em> (Publications)
OBJECTIVES: The pharmacokinetic (PK) parameters of artesunate, recently discovered to possess promising trematocidal activity, and its main metabolite dihydroartemisinin (DHA) were determined in rats
Activity of antiandrogens against juvenile and adult <em>Schistosoma mansoni </em>in mice (Publications)
Objectives The antischistosomal properties of the marketed antiandrogens bicalutamide, flutamide, nilutamide and cyproterone acetate were studied both in vivo and in vitro. Methods Schistosoma mansoni
Food-borne trematodiasis: current chemotherapy and advances with artemisinins and synthetic trioxolanes (Publications)
Over 40 million people are infected with food-borne trematodes and 750 million are at risk of food-borne trematodiasis, and yet this tropical disease is neglected. The current arsenal for the treatmen
Heteronuclear 19F-1H statistical total correlation spectroscopy as a tool in drug metabolism: study of flucloxacillin biotransformation (Publications)
We present a novel application of the heteronuclear statistical total correlation spectroscopy (HET-STOCSY) approach utilizing statistical correlation between one-dimensional 19F/1H NMR spectroscopic
Interactions of mefloquine with praziquantel in the <em>Schistosoma mansoni</em> mouse model and <em>in vitro</em> (Publications)
Objectives Mefloquine has interesting antischistosomal properties, hence it might be an attractive partner drug for combination treatment with praziquantel. The aim of this study was to evaluate activ