Pharmacometric analysis to describe pharmacokinetics and exposure-efficacy response of ivermectin in adolescents infected with <em>Trichuris... (Publications)
The efficacy of the combination therapy of albendazole and ivermectin against Trichuris trichiura infection is higher in Tanzania than in Côte d'Ivoire. This study therefore aimed to investigate the d
Feasibility and acceptability of the Problem Management for Moms programme for improving maternal mental health in Zambia: an open-label trial (Publications)
BACKGROUND: Psychological distress is common among mothers in low-income and middle-income countries, limiting their capacity to care for themselves and their children. This study aimed to test the fe
Malaria treatment for prevention: a modelling study of the impact of routine case management on malaria prevalence and burden (Publications)
BACKGROUND: Testing and treating symptomatic malaria cases is crucial for case management, but it may also prevent future illness by reducing mean infection duration. Measuring the impact of effective
Tambjamines as fast-acting multistage antimalarials (Publications)
Well-tolerated and novel antimalarials that can combat multiple stages of the parasite life cycle are desirable but challenging to discover and develop. Herein, we report results for natural product-i
One-year impact of behavioural interventions on schistosomiasis-related knowledge, attitude and practices of primary schoolchildren in Pemba, Tanzania (Publications)
BACKGROUND: Elimination of schistosomiasis as a public health problem and interruption of transmission in selected areas are goals set by the World Health Organization for 2030. Behaviour change commu
Ambient air pollution exposure and incidence of cataract surgery: the prospective 3City-Alienor study (Publications)
PURPOSE: Cataract, the leading cause of blindness worldwide, is a multifactorial disease involving oxidative stress mechanisms. The aim of our study was to investigate the relationship between air pol
Meteorological factors, population immunity, and COVID-19 incidence: a global multi-city analysis (Publications)
OBJECTIVES: While COVID-19 continues to challenge the world, meteorological variables are thought to impact COVID-19 transmission. Previous studies showed evidence of negative associations between hig
Praziquantel and factor H recruitment differentially affect the susceptibility of <em>Schistosoma mansoni</em> to complement-mediated damage (Publications)
BACKGROUND: Schistosomes are highly efficient evaders of human immunity, as evident by their ability to survive in human blood for years. How they protect themselves against the constant attack by a k
Efficacy and safety of albendazole alone versus albendazole in combination with ivermectin for the treatment of <em>Trichuris trichiura</em>... (Publications)
Trichuris trichiura, a soil-transmitted helminth (STH), often persists after a single dose of anthelminthic treatment. To overcome limited efficacy against T. trichiura of benzimidazoles (albendazole
