Multicentre harmonization and co-analysis for large-scale environmental epidemiology : combining environmental exposure and health datasets (Publications)
Background Like other branches of epidemiology and public health, environmental epidemiology faces the significant challenge of teasing out the health effects of a large number of interplaying risk fa
New acyl derivatives of 3-aminofurazanes and their antiplasmodial activities (Publications)
An N-acylated furazan-3-amine of a Medicines for Malaria Venture (MMV) project has shown activity against different strains of Plasmodium falciparum. Seventeen new derivatives were prepared and tested
Multiple air pollutant exposure and lung cancer in Tehran, Iran (Publications)
Lung cancer is the most rapidly increasing malignancy worldwide with an estimated 2.1 million cancer cases in the latest, 2018 World Health Organization (WHO) report. The objective of this study was t
3-Hydroxy-propanamidines, a new class of orally active antimalarials targeting <em>Plasmodium falciparum</em> (Publications)
3-Hydroxypropanamidines are a new promising class of highly active antiplasmodial agents. The most active compound 22 exhibited excellent antiplasmodial in vitro activity with nanomolar inhibition of
Melting the <em>eis</em>: non-detection of kanamycin resistance markers by routine diagnostic tests and identification of new <em>eis</em>-promoter... (Publications)
Eis-promoter mutations can confer reduced Mycobacterium tuberculosis kanamycin susceptibility. GenoType MTBDRsl, a widely used assay evaluating this region, wrongly classified 17/410 isolates as eis-p
The consequences of declining population access to insecticide-treated nets (ITNs) on net use patterns and physical degradation of nets after 22... (Publications)
BACKGROUND: As insecticide-treated nets (ITNs) wear out and are disposed, some household members are prioritized to use remaining ITNs. This study assessed how nets are allocated within households to
Spirombandakamine A3 and cyclombandakamines A8 and A9, polycyclic naphthylisoquinoline dimers, with antiprotozoal activity, from a Congolese... (Publications)
Spirombandakamine A3 (7) is only the third known naphthylisoquinoline dimer with a spiro-fused novel molecular framework and the first such representative to possess a relative trans-configuration at