Clinical characteristics and outcome of children hospitalized with scrub typhus in an area of endemicity (Publications)
BACKGROUND: Scrub typhus, caused by Orientia tsutsugamushi, is a major cause of acute febrile illness in children in the rural tropics. METHODS: We recruited 60 febrile pediatric patients with a posit
Synthesis and biological investigation of (+)-3-hydroxymethylartemisinin (Publications)
Herein, we describe a biomimetic entry to (+)-3-hydroxymethylartemisinin (2) as well as to the artemisinin derivatives (+)-3-hydroxymethyl-9-desmethylartemisinin (16) and (+)-3-hydroxymethyl-9-epi-art
Exposure to moderate air pollution and associations with lung function at school-age: a birth cohort study (Publications)
BACKGROUND: Adverse effects of higher air pollution levels before and after birth on subsequent lung function are often reported in the literature. We assessed whether low-to-moderate levels of air po
Evaluation of the sentinel surveillance system for influenza-like illnesses in the Greater Accra region, Ghana, 2018 (Publications)
BACKGROUND: Influenza-like Illness (ILI) is a medical diagnosis of possible influenza or another respiratory illness with a common set of symptoms. The deaths of four schoolchildren, during a pandemic
Measuring mobility, disease connectivity and individual risk: a review of using mobile phone data and mHealth for travel medicine (Publications)
RATIONALE FOR REVIEW: The increasing mobility of populations allows pathogens to move rapidly and far, making endemic or epidemic regions more connected to the rest of the world than at any time in hi
Epidemiological links between malaria parasitaemia and hypertension: findings from a population-based survey in rural Côte d'Ivoire (Publications)
BACKGROUND: Although potential links between malaria parasitaemia and hypertension have been hypothesized, there is paucity of epidemiologic evidence on this link. We investigated in a population-base
Design, synthesis, and biological evaluation of new 1-(Aryl-1<em>H</em>-pyrrolyl)(phenyl)methyl-1<em>H</em>-imidazole derivatives as antiprotozoal... (Publications)
We have designed and synthesized a series of new imidazole-based compounds structurally related to an antiprotozoal agent with nanomolar activity which we identified recently. The new analogs possess
New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries (Publications)
Reduced lung function predicts mortality and is key to the diagnosis of chronic obstructive pulmonary disease (COPD). In a genome-wide association study in 400,102 individuals of European ancestry, we
Depression and anxiety symptoms in cardiac patients: a cross-sectional hospital-based study in a Palestinian population (Publications)
BACKGROUND: Mental health problems have an adverse effect on the course of cardiac disease. The integration of their diagnosis and treatment into cardiology care is generally poor. It is particularly
Evaluating next-generation sequencing (NGS) methods for routine monitoring of wild bees: metabarcoding, mitogenomics or NGS barcoding (Publications)
Implementing cost-effective monitoring programs for wild bees remains challenging due to the high costs of sampling and specimen identification. To reduce costs, next generation sequencing (NGS)-based