New antiparasitic flexible triaryl diamidines, their prodrugs and aza analogues: synthesis, <em>in vitro</em> and<em> in vivo</em> biological... (Publications)
Dicationic diamidines have been well established as potent antiparasitic agents with proven activity against tropical diseases like trypanosomiasis and malaria. This work presents the synthesis of new
Primary care case management of febrile children: insights from the ePOCT routine care cohort in Dar es Salaam, Tanzania (Publications)
Aim: To provide insight in the primary health care (PHC) case management of febrile children under-five in Dar es Salaam, and to identify areas for improving quality of care. Methods: We used data fro
Spatial prediction of malaria prevalence in Papua New Guinea: a comparison of Bayesian decision network and multivariate regression modelling... (Publications)
BACKGROUND: Considerable progress towards controlling malaria has been made in Papua New Guinea through the national malaria control programme's free distribution of long-lasting insecticidal nets, im
Estimation of heat-attributable mortality using the cross-validated best temperature metric in Switzerland and South Korea (Publications)
This study presents a novel method for estimating the heat-attributable fractions (HAF) based on the cross-validated best temperature metric. We analyzed the association of eight temperature metrics (
Associations between natural resource extraction and incidence of acute and chronic health conditions: evidence from Tanzania (Publications)
Natural resource extraction projects are often accompanied by complex environmental and social-ecological changes. In this paper, we evaluated the association between commodity extraction and the inci
Diarrhoea among children aged under five years and risk factors in informal settlements: a cross-sectional study in Cape Town, South Africa (Publications)
Background: There is limited data on the association between diarrhoea among children aged under five years (U5D) and water use, sanitation, hygiene, and socio-economics factors in low-income communit
Association of livestock ownership and household dietary quality: results from a cross-sectional survey from rural India (Publications)
Studies from India and several eastern African countries found that the impact of dairy animal ownership on household nutrition varied greatly, depending on the socio-geographic context. The purpose o
Fostering cardiovascular health at work - case study from Senegal (Publications)
BACKGROUND: Of the 15 million annual premature deaths from non-communicable diseases (NCDs), 85% occur in low- and middle-income countries (LMICs). Affecting individuals in the prime of their lives, N
Efficacy and tolerability of quinacrine monotherapy and albendazole plus chloroquine combination therapy in nitroimidazole-refractory giardiasis: a... (Publications)
BACKGROUND: Giardiasis failing nitroimidazole first-line treatment is an emerging problem in returning European travelers. We present data on the efficacy and tolerability of 2 second-line treatment r