Soudanones A-G: antifungal isochromanones from the ascomycetous fungus <em>Cadophora</em> sp. isolated from an iron mine (Publications)
One new isochromane (pseudoanguillosporin C, 2), seven isochromanones (soudanones A-G, 3-9), and six known analogues including 10 and 11 were isolated from a culture of the fungus Cadophora sp. 10-5-2
<em>In vivo</em> biosynthesis of terpene nucleosides provides unique chemical markers of <em>Mycobacterium tuberculosis</em> infection (Publications)
Although small molecules shed from pathogens are widely used to diagnose infection, such tests have not been widely implemented for tuberculosis. Here we show that the recently identified compound, 1-
Host-directed therapies for tackling multi-drug resistant TB - learning from the Pasteur-Bechamp debates (Publications)
Tuberculosis (TB) remains a global emergency causing an estimated 1.5 million deaths annually. For several decades the major focus of TB treatment has been on antibiotic development targeting Mycobact
Chemical constituents from <em>Waltheria indica</em> exert <em>in vitro</em> activity against <em>Trypanosoma brucei</em> and <em>T. cruzi</em> (Publications)
Six extracts from the roots and the aerial parts of Waltheria indica L. (Malvaceae) were screened for their in vitro antitrypanosomal activity towards Trypanosoma brucei brucei STIB 427 strain, Trypan
Towards host-directed therapies for tuberculosis [Comment] (Publications)
The treatment of tuberculosis is based on combinations of drugs that directly target Mycobacterium tuberculosis. A new global initiative is now focusing on a complementary approach of developing adjun
