Two new rapid SNP-typing methods for classifying <em>Mycobacterium tuberculosis</em> complex into the main phylogenetic lineages (Publications)
There is increasing evidence that strain variation in Mycobacterium tuberculosis complex (MTBC) might influence the outcome of tuberculosis infection and disease. To assess genotype-phenotype associat
A research agenda for malaria eradication: diagnoses and diagnostics (Publications)
Many of malaria's signs and symptoms are indistinguishable from those of other febrile diseases. Detection of the presence of Plasmodium parasites is essential, therefore, to guide case management. Im
Comparative cost assessment of the Kato-Katz and FLOTAC techniques for soil-transmitted helminth diagnosis in epidemiological surveys (Publications)
ABSTRACT: BACKGROUND: The Kato-Katz technique is widely used for the diagnosis of soil-transmitted helminthiasis in epidemiological surveys and is believed to be an inexpensive method. The FLOTAC tech
Tribendimidine and albendazole for treating soil-transmitted helminths, <em>Strongyloides stercoralis</em> and <em>Taenia</em> spp.: open-label... (Publications)
BACKGROUND: Tribendimidine is an anthelminthic drug with a broad spectrum of activity. In 2004 the drug was approved by Chinese authorities for human use. The efficacy of tribendimidine against soil-t
Design and pre-clinical profiling of a <em>Plasmodium falciparum</em> MSP-3 derived component for a multi-valent virosomal malaria vaccine (Publications)
BACKGROUND: Clinical profiling of two components for a synthetic peptide-based virosomal malaria vaccine has yielded promising results, encouraging the search for additional components for inclusion i
Studies on the mechanisms supporting the continuous growth of <em>Trypanosoma (Trypanozoon) brucei</em> as bloodstream-like form in vitro (Publications)
The conditions which enable growth of Trypanosoma (T.) brucei stock S 427 as bloodstream-like form over bovine fibroblast-like cells (BHF) were analyzed. The experiments with different BHF conditioned
FlexiChip package: an universal microarray with a dedicated analysis software for high-thoughput SNPs detection linked to anti-malarial drug... (Publications)
BACKGROUND: A number of molecular tools have been developed to monitor the emergence and spread of anti-malarial drug resistance to Plasmodium falciparum. One of the major obstacles to the wider imple
Intermittent preventive treatment for malaria in Papua New Guinean infants exposed to <em>Plasmodium falciparum</em> and <em>P. vivax</em>: a... (Publications)
BACKGROUND: Intermittent preventive treatment in infants (IPTi) has been shown in randomized trials to reduce malaria-related morbidity in African infants living in areas of high Plasmodium falciparum