The pharmacokinetics and drug-drug interactions of ivermectin in <em>Aedes aegypti</em> mosquitoes (Publications)
Mosquitoes are vectors of major diseases such as dengue fever and malaria. Mass drug administration of endectocides to humans and livestock is a promising complementary approach to current insecticide
Antiprotozoal structure-activity relationships of synthetic leucinostatin derivatives and elucidation of their mode of action (Publications)
Leucinostatin A is one of the most potent antiprotozoal compounds ever described, but little was known on structure-activity relationships (SAR). We used Trypanosoma brucei as a protozoal model organi
A systematic review and an individual patient data meta-analysis of ivermectin use in children weighing less than fifteen kilograms: is it time to... (Publications)
BACKGROUND: Oral ivermectin is a safe broad spectrum anthelminthic used for treating several neglected tropical diseases (NTDs). Currently, ivermectin use is contraindicated in children weighing less
Variation in calculating and reporting antimalarial efficacy against<em> Plasmodium falciparum</em> in sub-Saharan Africa: a systematic review of... (Publications)
Antimalarials, in particular artemisinin-based combination therapies (ACTs), are critical tools in reducing the global burden of malaria, which is concentrated in sub-Saharan Africa. Performing and re
Variants associated with <em>HHIP</em> expression have sex-differential effects on lung function (Publications)
Background: Lung function is highly heritable and differs between the sexes throughout life. However, little is known about sex-differential genetic effects on lung function. We aimed to conduct the f
Exposure to multiple pesticides and neurobehavioral outcomes among smallholder farmers in Uganda (Publications)
BACKGROUND: Multiple epidemiological studies have shown that exposure to single pesticide active ingredients or chemical groups is associated with adverse neurobehavioral outcomes in farmers. In agric
Is universal health coverage affordable? Estimated costs and fiscal space analysis for the Ethiopian essential health services package (Publications)
Estimating the required resources for implementing an essential health services package (EHSP) is vital to examine its feasibility and affordability. This study aimed to estimate the financial resourc
A modular framework for the development of targeted Covid-19 blood transcript profiling panels (Publications)
BACKGROUND: Covid-19 morbidity and mortality are associated with a dysregulated immune response. Tools are needed to enhance existing immune profiling capabilities in affected patients. Here we aimed
Semi-field evaluation of freestanding transfluthrin passive emanators and the BG sentinel trap as a "push-pull control strategy" against <em>Aedes... (Publications)
BACKGROUND: Spatial repellents that drive mosquitoes away from treated areas, and odour-baited traps, that attract and kill mosquitoes, can be combined and work synergistically in a push-pull system.
Developing an SMS text message intervention on sexual and reproductive health with adolescents and youth in Peru (Publications)
BACKGROUND: Improved access to sexual and reproductive health (SRH) services and information is essential for supporting adolescents and youth in making informed decisions and optimizing each young pe
