Incomplete<em> Plasmodium falciparum</em> growth inhibition following piperaquine treatment translates into increased parasite viability in the <em>in... (Publications)
Antimalarial resistance to the first-line partner drug piperaquine (PPQ) threatens the effectiveness of artemisinin-based combination therapy. In vitro piperaquine resistance is characterized by incom
Association between concurrence of multiple risk factors and under-5 mortality: a pooled analysis of data from demographic and health survey in 61... (Publications)
BACKGROUND: Exposure to multiple risk factors is prevalent in low-and middle-income countries (LMICs), challenging one-directional strategies to address preventable under-5 mortality (U5M). This study
Long-term development of loneliness in older people and associations with stringency of COVID-19 measures: an observational cohort study (Publications)
BACKGROUND: Most longitudinal studies found heightened feelings of loneliness in older people in spring 2020 compared to times before the pandemic. However, longer-term effects are more disputed. We,
The acute effects of community violence on young children's regulatory, behavioral, and developmental outcomes in a low-income urban sample in... (Publications)
BACKGROUND: Existing research on the impacts of adversity on young children's psychological well-being has largely focused on household-level risk factors using observational methods in high-income co
Comparing pharmacy practice in health facilities with and without pharmaceutically trained dispensers: a post intervention study in Tanzania (Publications)
BACKGROUND: The critical shortage of comprehensively trained healthcare staff in Tanzania affects the capacity to deliver essential health services, attain universal health coverage and compromises he
Inhibition of <em>Leishmania donovani</em> transformation by hamster spleen homogenates and active human lymphocytes (Publications)
HAEMOFLAGELLATES are protozoan parasites responsible for many important diseases of man and domestic animals1. Leishmania donovani, the cause of visceral leishmaniasis or kala azar, is a widespread hu
The essential malaria protein <em>Pf</em>CyRPA targets glycans to invade erythrocytes (Publications)
Summary Plasmodium falciparum is a human-adapted apicomplexan parasite that causes the most dangerous form of malaria. P. falciparum cysteine-rich protective antigen (PfCyRPA) is an invasion complex p
Heterogeneities in the transmission of infectious agents: implications for the design of control programs (Publications)
From an analysis of the distributions of measures of transmission rates among hosts, we identify an empirical relationship suggesting that, typically, 20% of the host population contributes at least 8
