Genotyping methods to distinguish <em>Plasmodium falciparum</em> recrudescence from new infection for the assessment of antimalarial drug efficacy: an... (Publications)
BACKGROUND: Distinguishing Plasmodium falciparum recrudescence from new infections is crucial for the assessment of antimalarial drug efficacy against P falciparum. We aimed to compare the efficacy of
The non-inferiority of piperonyl-butoxide Yorkool® G3 insecticide-treated nets compared to Olyset®Plus measured by <em>Anopheles arabiensis</em>... (Publications)
BACKGROUND: Non-inferiority trials are recommended by the World Health Organization (WHO) to demonstrate that health products show comparable efficacy to that of existing standard of care. As part of
Single-dose drug development candidate for schistosomiasis (Publications)
Aryl hydantoins were identified in the early 1980s as a promising antischistosomal chemotype. However, as exemplified by Ro 13-3978, this compound series produced antiandrogenic side effects on the ho
Soliciting diaries for "real-time" insights into the COVID-19 pandemic: methodological reflections on using digital technologies to engage the public (Publications)
OBJECTIVES: To discuss the opportunities and challenges of the qualitative solicited diary approach using digital technologies as an innovative way to access insights into people's lives and their uni
A novel barcoded nanopore sequencing workflow of high-quality, full-length bacterial 16S amplicons for taxonomic annotation of bacterial isolates and... (Publications)
Due to recent improvements, Nanopore sequencing has become a promising method for experiments relying on amplicon sequencing. We describe a flexible workflow to generate and annotate high-quality, ful
Characteristics, consent patterns, and challenges of randomized trials using the Trials within Cohorts (TwiCs) design: a scoping review (Publications)
OBJECTIVES: Trials within Cohorts (TwiCs) is a pragmatic design approach that may overcome frequent challenges of traditional randomized trials such as slow recruitment, burdensome consent procedures,
Does growing up in a physical activity-friendly neighborhood increase the likelihood of remaining active during adolescence and early adulthood? (Publications)
BACKGROUND: The SOPHYA-cohort-study investigated whether the objectively characterized and perceived residential neighborhood of Swiss youth predict accelerometer-measured physical activity and activi
Patient's willingness to pay for improved community health insurance in Tanzania (Publications)
Globally, achieving universal health coverage remains significant challenge. Health insurance coverage in low- and middle-income countries is still low with only a few African countries managed to rea