A large <em>Plasmodium vivax</em> reservoir and little population structure in the South Pacific (Publications)
INTRODUCTION: The importance of Plasmodium vivax in malaria elimination is increasingly being recognized, yet little is known about its population size and population genetic structure in the South Pa
The cell wall-associated mycolactone polyketide synthases are necessary but not sufficient for mycolactone biosynthesis (Publications)
Mycolactones are polyketide-derived lipid virulence factors made by the slow-growing human pathogen, Mycobacterium ulcerans. Three unusually large and homologous plasmid-borne genes (mlsA1: 51 kb, mls
Differences in primary sites of infection between zoonotic and human tuberculosis: results from a worldwide systematic review (Publications)
Tuberculosis (TB) is one of the most devastating infectious diseases worldwide. Whilst global burden estimates for M. tuberculosis infection (MtTB) are well established, accurate data on the contribut
<em>Strongyloides stercoralis</em> is a cause of abdominal pain, diarrhea and urticaria in rural Cambodia (Publications)
BACKGROUND: We document clinical manifestations of 21 patients heavily infected with S. stercoralis (more than 250 larvae in a single Baermann test) from a community in rural Cambodia, both before and
Population pharmacokinetics of mefloquine, piperaquine and artemether-lumefantrine in Cambodian and Tanzanian malaria patients (Publications)
BACKGROUND: Inter-individual variability in plasma concentration-time profiles might contribute to differences in anti-malarial treatment response. This study investigated the pharmacokinetics of thre