Efficacy and safety of intermittent preventive treatment with sulfadoxine-pyrimethamine for malaria in African infants: a pooled analysis of six... (Publications)
BACKGROUND: Intermittent preventive treatment (IPT) is a promising strategy for malaria control in infants. We undertook a pooled analysis of the safety and efficacy of IPT in infants (IPTi) with sulf
Potent inhibitors of malarial aspartic proteases, the plasmepsins, by hydroformylation of substituted 7-azanorbornenes (Publications)
The increasing prevalence of multidrug-resistant strains of the malarial parasite Plasmodium falciparum requires the urgent development of new therapeutic agents with novel modes of action. The vacuol
Synthesis and antiprotozoal activity of pyridyl analogues of pentamidine (Publications)
A series of novel pyridyl analogues 1-18 of antiprotozoal drug 1,5-bis(4-amidinophenoxy)pentane (pentamidine) has been synthesized and tested for in vitro activities against Trypanosoma brucei rhodesi
Synthesis and antiprotozoal activity of cationic 2-phenylbenzofurans (Publications)
A series of cationically substituted 2-phenylbenzofurans 1- 49 have been synthesized, and their in vitro antiprotozoal properties against Trypanosoma brucei rhodesiense, Plasmodium falciparum, and Lei
Bayesian spatial risk prediction of <em>Schistosoma mansoni</em> infection in western Côte d'Ivoire using a remotely-sensed digital elevation... (Publications)
An important epidemiologic feature of schistosomiasis is the focal distribution of the disease. Thus, the identification of high-risk communities is an essential first step for targeting interventions
Melarsoprol- and pentamidine-resistant <em>Trypanosoma brucei rhodesiense</em> populations and their cross-resistance (Publications)
Resistance to melarsoprol and pentamidine was induced in bloodstream-form Trypanosoma brucei rhodesiense STIB 900 in vitro, and drug sensitivity was determined for melarsoprol, pentamidine and furamid
