A novel BACE inhibitor NB-360 shows a superior pharmacological profile and robust reduction of amyloid-beta and neuroinflammation in APP transgenic... (Publications)
BACKGROUND: Alzheimer's disease (AD) is the most common form of dementia, the number of affected individuals is rising, with significant impacts for healthcare systems. Current symptomatic treatments
Childhood illness prevalence and health seeking behavior patterns in rural Tanzania (Publications)
INTRODUCTION: This paper identifies factors influencing differences in the prevalence of diarrhea, fever and acute respiratory infection (ARI), and health seeking behavior among caregivers of children
Bifidobacteria strains isolated from stools of iron deficient infants can efficiently sequester iron (Publications)
BACKGROUND: Bifidobacteria is one of the major gut commensal groups found in infants. Their colonization is commonly associated with beneficial effects to the host through mechanisms like niche occupa
Strategies and approaches to vector control in nine malaria-eliminating countries: a cross-case study analysis (Publications)
BACKGROUND: There has been progress towards malaria elimination in the last decade. In response, WHO launched the Global Technical Strategy (GTS), in which vector surveillance and control play importa
Distribution and transmission of <em>Mycobacterium tuberculosis</em> complex lineages among children in peri-urban Kampala, Uganda (Publications)
BACKGROUND: To gain insight into the transmission of tuberculosis (TB) in peri-urban Kampala-Uganda, we performed a household contact study using children as a surrogate for recent transmission of Myc
Accuracy of assessment of eligibility for early medical abortion by community health workers in Ethiopia, India and South Africa (Publications)
OBJECTIVE: To assess the accuracy of assessment of eligibility for early medical abortion by community health workers using a simple checklist toolkit. DESIGN: Diagnostic accuracy study. SETTING: Ethi
Biomarkers of host response predict primary end-point radiological pneumonia in Tanzanian children with clinical pneumonia: a prospective cohort study (Publications)
BACKGROUND: Diagnosing pediatric pneumonia is challenging in low-resource settings. The World Health Organization (WHO) has defined primary end-point radiological pneumonia for use in epidemiological
Experience and lessons from health impact assessment for human rights impact assessment (Publications)
As globalisation has opened remote parts of the world to foreign investment, global leaders at the United Nations and beyond have called on multinational companies to foresee and mitigate negative imp