Ancistrotanzanine A, the first 5,3'-coupled naphthylisoquinoline alkaloid, and two further, 5,8'-linked related compounds from the newly described... (Publications)
The first phytochemical investigation of the recently discovered East African liana Ancistrocladus tanzaniensis is described, resulting in the isolation and structural elucidation of two new naphthyli
Assessment of intensity, prevalence and duration of everyday activities in Swiss school children: a cross-sectional analysis of accelerometer and... (Publications)
ABSTRACT: BACKGROUND: Appropriately measuring habitual physical activity (PA) in children is a major challenge. Questionnaires and accelerometers are the most widely used instruments but both have wel
Nonirritant intradermal skin test concentrations of ciprofloxacin, clarithromycin, and rifampicin (Publications)
BACKGROUND: Intradermal skin testing of the clinically important antibiotics ciprofloxacin, clarithromycin, and rifampicin in the case of suspected allergies to antibiotics is poorly standardized. For
Synthesis of a potent antimalarial agent through natural products conjugation (Publications)
Au naturel! (+)-Usnic acid (green) is a weak antimalarial agent, however, in conjugation with known antimalarial scaffolds and drugs, such as dihydroartemisinin (blue), potent activity against the blo
Highly selective antiplasmodial naphthylisoquinoline alkaloids from <em>Ancistrocladus tectorius</em> (Publications)
Naphthylisoquinoline alkaloids, named ancistectorine A(1), N-methylancistectorine A(1), ancistectorine A(2), 5-epi-ancistectorine A(2), ancistectorine A(3), ancistectorine B(1), and ancistectorine C(1
Chicken egg yolk antibodies (IgY) for detecting circulating antigens of <em>Schistosoma japonicum</em> (Publications)
BACKGROUND: IgY isolated from egg yolk has been widely used in immunodiagnostic tests, including tests to detect circulating antigen (soluble egg antigen or SEA) of Schistosoma japonicum. RESULTS: A s
Antimalarial beta-carbolines from the New Zealand ascidian<em> Pseudodistoma opacum</em> (Publications)
One tetrahydro-beta-carboline, (-)-7-bromohomotrypargine (1), and three alkylguanidine-substituted beta-carbolines, opacalines A, B, and C (2-4), have been isolated from the New Zealand ascidian Pseud
Intratumoral plasmacytoid dendritic cells associate with increased survival in patients with follicular lymphoma (Publications)
Gene array studies on follicular lymphoma (FL) have associated non-malignant tumor-infiltrating immune cells with patient survival. We examined the role of such cells detectable by immunohistochemistr