Benzimidazole analogues active against adult <em>Schistosoma mansoni</em>: SAR analyses, <em>in vivo </em>efficacy in mice, and preliminary... (Publications)
For over three decades, praziquantel (PZQ) has been the mainstay chemotherapy for prevention and treatment of schistosomiasis. The excessive use of PZQ, coupled with the lack of advanced drug candidat
Schistosomiasis and water resources development: systematic review, meta-analysis, and estimates of people at risk (Publications)
An estimated 779 million people are at risk of schistosomiasis, of whom 106 million (13.6%) live in irrigation schemes or in close proximity to large dam reservoirs. We identified 58 studies that exam
A cluster randomized trial assessing the effect of a digital health algorithm on quality of care in Tanzania (DYNAMIC study) (Publications)
Digital clinical decision support tools have contributed to improved quality of care at primary care level health facilities. However, data from real-world randomized trials are lacking. We conducted
A matter of timing: biting by malaria-infected <em>Anopheles</em> mosquitoes and the use of interventions during the night in rural south-eastern... (Publications)
Knowing when and where infected mosquitoes bite is required for estimating accurate measures of malaria risk, assessing outdoor exposure, and designing intervention strategies. This study combines sec
Estimating the burden of disease attributable to non-assisted suicide in Switzerland from 2009 to 2021: a secondary data analysis (Publications)
CONTEXT AND GOAL: This research addresses the issue of suicide and attempted suicide, which have a significant impact on global premature mortality and disability. Particularly noteworthy is the preva
Viral suppression and adherence in adolescents living with HIV in rural Tanzania (Publications)
BACKGROUND: Adolescents living with HIV (ALHIV) in sub-Saharan Africa are affected by poor treatment outcomes, likely a consequence of poor adherence. OBJECTIVES: To assess viral suppression rates and
One Health (Publications)
One Health is an integrated approach to the health of people, animals and the environment simultaneously. An integrated view of human and environmental health is not new and has roots in India and Chi