Sachet water quality and product registration: a cross-sectional study in Accra, Ghana (Publications)
The study's objectives were to assess the extent to which packaged water producers follow product registration procedures and to assess the relationship between product registration and drinking water
Spontaneous point mutations in the capsule synthesis locus leading to structural and functional changes of the capsule in serogroup A meningococcal... (Publications)
Whole genome sequencing analysis of 100 Neisseria meningitidis serogroup A isolates has revealed that the csaABCD-ctrABCD-ctrEF capsule polysaccharide synthesis locus represents a spontaneous point mu
Loss of genomic diversity in a <em>Neisseria meningitidis</em> clone through a colonization bottleneck (Publications)
Neisseria meningitidis is the leading cause of epidemic meningitis in the 'meningitis belt' of Africa, where clonal waves of colonization and disease are observed. Point mutations and horizontal gene
Expanding the rubterolone family: intrinsic reactivity and directed diversification of PKS-derived pyrans (Publications)
We characterized two key biosynthetic intermediates of the intriguing rubterolone family (tropolone alkaloids) that contain a highly reactive pyran moiety (in equilibrium with the hydrolyzed 1,5-dione
Fostering population-based cohort data discovery: the Maelstrom Research cataloguing toolkit (Publications)
BACKGROUND: The lack of accessible and structured documentation creates major barriers for investigators interested in understanding, properly interpreting and analyzing cohort data and biological sam
Virus detection by high-throughput sequencing of small RNAs: large scale performance testing of sequence analysis strategies (Publications)
Recent developments in high-throughput sequencing (HTS), also called next-generation sequencing (NGS), technologies and bioinformatics have drastically changed research on viral pathogens and spurred
Diagnostic comparison of Baermann funnel, Koga agar plate culture and polymerase chain reaction for detection of human <em>Strongyloides... (Publications)
Human infection with the nematode Strongyloides stercoralis, which may have a life-threatening course, primarily occurs in tropical settings. Epidemiological data on the occurrence of strongyloidiasis
Particulate matter air pollution components and incidence of cancers of the stomach and the upper aerodigestive tract in the European Study of Cohorts... (Publications)
INTRODUCTION: Previous analysis from the large European multicentre ESCAPE study showed an association of ambient particulate matter
Acute phase proteins and IP-10 as triage tests for the diagnosis of tuberculosis: a systematic review and meta-analysis (Publications)
OBJECTIVES: We examined the data reported in studies for diagnostic purposes and discuss whether their intended use could be extended to triage, as rule in or rule out tests to select individuals who
