Using a <em>Madurella mycetomatis</em> specific PCR on grains obtained via non-invasive fine needle aspirated material is more accurate than cytology (Publications)
BACKGROUND: Eumycetoma is a chronic subcutaneous inflammatory fungal infection most often caused by Madurella mycetomatis. Using a species-specific PCR on DNA directly isolated from grains is currentl
Non-optimal apparent temperature and cardiovascular mortality: the association in Puducherry, India between 2011 and 2020 (Publications)
BACKGROUND: Cardiovascular diseases (CVDs), the leading cause of death worldwide, are sensitive to temperature. In light of the reported climate change trends, it is important to understand the burden
Childhood adversity and educational attainment: evidence from Zambia on the role of personality (Publications)
INTRODUCTION: We examine whether personality traits mediate the association between childhood adversity and educational attainment using longitudinal data from a cohort in Zambia. METHODS: We fit a st
Simulation-based assessment of cholera epidemic response: a case study of Al-Hudaydah, Yemen (Publications)
Cholera kills between 21,000 and 143,000 people globally each year. It is often fatal, killing up to 50% of the severely symptomatic patients; but death by cholera is preventable with timely treatment
Health and economic benefits of achieving contraceptive and maternal health targets in small island developing states in the Pacific and Caribbean (Publications)
INTRODUCTION: Reducing unmet need for modern contraception and expanding access to quality maternal health (MH) services are priorities for improving women's health and economic empowerment. To suppor
Epidemiology of pediatric schistosomiasis in hard-to-reach areas and populations: a scoping review protocol (Publications)
Background: Schistosomiasis is a neglected tropical disease (NTD) that affects millions of people. Children are the most vulnerable group to developing overt disease. An estimated 779 million people a
Fast-killing tyrosine amide ((<em>S</em>)-SW228703) with blood- and liver-stage antimalarial activity associated with the cyclic amine resistance... (Publications)
Current malaria treatments are threatened by drug resistance, and new drugs are urgently needed. In a phenotypic screen for new antimalarials, we identified (S)-SW228703 ((S)-SW703), a tyrosine amide
Detection of mostly viral pathogens and high proportion of antibiotic treatment initiation in hospitalised children with community-acquired pneumonia... (Publications)
AIMS OF THE STUDY: Globally, since the introduction of conjugate-vaccines against encapsulated bacteria, respiratory viruses have caused most hospitalisations for community-acquired pneumonia. The aim
<em>In vitro</em> and <em>in vivo</em> antischistosomal activity profiling and pharmacokinetics of ozonide carboxylic acids (Publications)
Praziquantel, the only drug in clinical use for the treatment and control of schistosomiasis, is inactive against developing infections. Ozonides are synthetic peroxide derivatives inspired by the nat
