Effects of filter choice in GT3X accelerometer assessments of free-living activity (Publications)
PURPOSE: Actigraph accelerometers are widely used devices to objectively assess physical activity. The GT3X version has two filter options to be selected prior to data assessment (normal and low frequ
Predictors of methacholine responsiveness in a general population (Publications)
OBJECTIVE: Methacholine responsiveness is an end point widely used in epidemiologic studies of asthma. This study aims to quantify the relative importance of different predictors of responsiveness suc
What physical activity surveillance needs: validity of a single-item questionnaire (Publications)
BACKGROUND: Self-report instruments to assess physical activity are still the most feasible option in many population-wide surveys, and often need to be very short owing to resource constraints. The a
Glutathione S-transferase polymorphisms, passive smoking, obesity, and heart rate variability in nonsmokers (Publications)
BACKGROUND: Disturbances of heart rate variability (HRV) may represent one pathway by which second-hand smoke (SHS) and air pollutants affect cardiovascular morbidity and mortality. The mechanisms are
Ten-year follow-up of cluster-based asthma phenotypes in adults: a pooled analysis of three cohorts (Publications)
Rationale: The temporal stability of adult asthma phenotypes identified using clustering methods has never been addressed. Longitudinal cluster-based methods may provide novel insights in the study of
Clinical diagnosis of current asthma: predictive value of respiratory symptoms in the SAPALDIA study. Swiss Study on Air Pollution and Lung Diseases... (Publications)
Bronchial asthma is a very common disease which often remains underdiagnosed. The aim of this study was to determine the predictive value of the most common respiratory symptoms and to explore the bes
Exposure to motor vehicle traffic and allergic sensitization. The Swiss Study on Air Pollution and Lung Diseases in Adults (SAPALDIA) Team (Publications)
We examined the association between the presence of an allergic sensitization and seasonal allergic diseases or symptoms and the exposure to road traffic in Basel, Switzerland. Traffic counts at the d
Associations between lung function and estimated average exposure to NO2 in eight areas of Switzerland (Publications)
In this paper, we present results from the SAPALDIA study (Swiss Study on Air Pollution and Lung Diseases in Adults) regarding associations between lung function [forced vital capacity (FVC) and force
<em>SERPINA1</em> gene variants in individuals from the general population with reduced {alpha}1-antitrypsin concentrations (Publications)
BACKGROUND: Individuals with severe deficiency in serum alpha1-antitrypsin (AAT) concentrations are at high risk for developing chronic obstructive pulmonary disease (COPD), whereas those carrying the