Structure elucidation and antimalarial activity of apicidin F: an apicidin-like compound produced by <em>Fusarium fujikuroi</em> (Publications)
Apicidins are cyclic tetrapeptides with histone deacetylase inhibitory activity. Since their discovery in 1996 a multitude of studies concerning the activity against protozoa and certain cancer cell l
Simple variables predict miserable outcome after intravenous thrombolysis (Publications)
BACKGROUND AND PURPOSE: To test the predictability of miserable outcome amongst ischaemic stroke patients receiving intravenous thrombolysis (IVT) based on a simple variables model (SVM) and to compar
The policy of free healthcare for children under the age of 6 years in Vietnam: assessment of the uptake for children hospitalised with acute... (Publications)
OBJECTIVE: To assess the proportion of, and reasons for, households not utilising the policy of free healthcare for children under 6 years of age (FCCU6) for hospitalisation with diarrhoea, and assess
<em>In silico</em> prediction and experimental evaluation of furanoheliangolide sesquiterpene lactones as potent agents against <em>Trypanosoma brucei... (Publications)
In continuation of our earlier study on the in vitro antiprotozoal activity of 40 natural sesquiterpene lactones (STLs), we extended the set of tested compounds from our laboratories to 59. On the bas
DMSO-mediated ligand dissociation: renaissance for biological activity of <em>N</em>-heterocyclic-[Ru(n6-arene)CI2] drug candidates (Publications)
Slipped under the radar? 1 H NMR spectroscopic examination revealed that [Ru(?6 -arene)Cl2 (L)] (L=N-heterocyclic ligands) complexes readily undergo ligand exchange reaction in DMSO, a popular medium
Improved services to enrollees into an HIV rural care and treatment center in Tanzania [Short communication] (Publications)
Better quality of services is essential for the sustainability of HIV programs, in particular in rural Sub-Saharan Africa, to support the increasing number of individuals treated with combination anti
In vitro and in vivo characterization of the antimalarial lead compound SSJ-183 in <em>Plasmodium</em> models (Publications)
The objective of this work was to characterize the in vitro (Plasmodium falciparum) and in vivo (Plasmodium berghei) activity profile of the recently discovered lead compound SSJ-183. The molecule sho