Efficacy and safety of praziquantel against light infections of <em>Opisthorchis viverrini</em>: a randomised parallel single blind dose-ranging trial (Publications)
BACKGROUND: The liver fluke Opisthorchis viverrini, highly prevalent in Southeast Asia, is an important public health burden, including a risk factor for developing an aggressive bile duct cancer, cho
Elimination of <em>Schistosoma mansoni</em> in infected mice by slow release of artemisone (Publications)
The current treatment of schistosomiasis is based on the anti-helminthic drug praziquantel (PZQ). PZQ affects only the adult stages of schistosomes. In addition, resistance to PZQ is emerging. We sugg
Associations between selective attention and soil-transmitted helminth infections, socioeconomic status, and physical fitness in disadvantaged... (Publications)
BACKGROUND: Socioeconomically deprived children are at increased risk of ill-health associated with sedentary behavior, malnutrition, and helminth infection. The resulting reduced physical fitness, gr
Improving household air, drinking water and hygiene in rural Peru: a community-randomized-controlled trial of an integrated environmental home-based... (Publications)
BACKGROUND: Diarrhoea and acute lower respiratory infections are leading causes of childhood morbidity and mortality, which can be prevented by simple low-cost interventions. Integrated strategies can
Genome-wide interaction analysis of air pollution exposure and childhood asthma with functional follow-up (Publications)
RATIONALE: The evidence supporting an association between traffic-related air pollution exposure and incident childhood asthma is inconsistent, and may depend on genetic factors. OBJECTIVES: To identi
Western European land use regression incorporating satellite- and ground-based measurements of NO2 and PM10 (Publications)
Land use regression (LUR) models typically investigate within-urban variability in air pollution. Recent improvements in data quality and availability, including satellite-derived pollutant measuremen
A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample (Publications)
RATIONALE: Lung function measures are heritable traits that predict population morbidity and mortality and are essential for the diagnosis of chronic obstructive pulmonary disease (COPD). Variations i
Genome-wide association study identifies five loci associated with lung function (Publications)
Pulmonary function measures are heritable traits that predict morbidity and mortality and define chronic obstructive pulmonary disease (COPD). We tested genome-wide association with forced expiratory
