Preventing leprosy with retrospective active case finding combined with single-dose rifampicin for contacts in a low endemic setting: results of the... (Publications)
Post-exposure prophylaxis (PEP) with single-dose rifampicin (SDR) reduces the risk of developing leprosy among contacts of leprosy patients. Most evidence for the feasibility of the intervention is fr
A descriptive qualitative case study of the experiences, perceptions, and attitudes of pregnant women on Unguja island, Zanzibar, towards... (Publications)
Many countries exclude pregnant and lactating women from mass drug administration (MDA) programmes with praziquantel against schistosomiasis due to historic safety concerns over drug use during gestat
Cancer risk in adolescents and young adults living with HIV in South Africa: a nationwide cohort study (Publications)
BACKGROUND: Literature on cancer in adolescents and young adults (AYA; aged 15-24 years) living with HIV is scarce. We studied cancer incidence in AYA living with HIV in South Africa between 2004 and
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation (Publications)
Characterizing genetic influences on DNA methylation (DNAm) provides an opportunity to understand mechanisms underpinning gene regulation and disease. In the present study, we describe results of DNAm
Nucleic acid amplification techniques for the detection of <em>Schistosoma mansoni</em> infection in humans and the intermediate snail host: a... (Publications)
BACKGROUND: Schistosomiasis is a parasitic disease caused by hematodes of genus Schistosoma. This review evaluated the available nucleic acid amplification techniques for diagnosing S. mansoni infecti
Discovery of novel antischistosomal scaffolds from the open access Pandemic Response Box (Publications)
BACKGROUND: Treatment and control of schistosomiasis rely on a single drug, praziquantel. New orally active antischistosomals featuring novel molecular scaffolds are urgently needed to prevent the eme
Sustainability of a school-based health intervention for prevention of non-communicable diseases in marginalised communities: protocol for a... (Publications)
INTRODUCTION: The prevalence of chronic, lifestyle-related diseases is increasing among adults and children from low-income and middle-income countries. Despite the effectiveness of community-based in