<em>Trypanosoma brucei gambiense</em> group 1 is distinguished by a unique amino acid substitution in the HpHb receptor implicated in human serum... (Publications)
Trypanosoma brucei rhodesiense (Tbr) and T. b. gambiense (Tbg), causative agents of Human African Trypanosomiasis (sleeping sickness) in Africa, have evolved alternative mechanisms of resisting the ac
Oral cholera vaccine use in Zanzibar: socioeconomic and behavioural features affecting demand and acceptance (Publications)
BACKGROUND: Cholera remains a serious public health problem in low-income countries despite efforts in the past to promote oral rehydration therapy as major treatment. In 2007, the majority of worldwi
Design and pre-clinical profiling of a <em>Plasmodium falciparum</em> MSP-3 derived component for a multi-valent virosomal malaria vaccine (Publications)
BACKGROUND: Clinical profiling of two components for a synthetic peptide-based virosomal malaria vaccine has yielded promising results, encouraging the search for additional components for inclusion i
Simulation of malaria epidemiology and control in the highlands of western Kenya (Publications)
BACKGROUND: Models of Plasmodium falciparum malaria epidemiology that provide realistic quantitative predictions of likely epidemiological outcomes of existing vector control strategies have the poten
Tribendimidine and albendazole for treating soil-transmitted helminths, <em>Strongyloides stercoralis</em> and <em>Taenia</em> spp.: open-label... (Publications)
BACKGROUND: Tribendimidine is an anthelminthic drug with a broad spectrum of activity. In 2004 the drug was approved by Chinese authorities for human use. The efficacy of tribendimidine against soil-t
Population hemoglobin mean and anemia prevalence in Papua New Guinea: new metrics for defining malaria endemicity? (Publications)
BACKGROUND: The hypothesis is that hemoglobin-based metrics are useful tools for estimating malaria endemicity and for monitoring malaria control strategies. The aim of this study is to compare popula
Comparative cost assessment of the Kato-Katz and FLOTAC techniques for soil-transmitted helminth diagnosis in epidemiological surveys (Publications)
ABSTRACT: BACKGROUND: The Kato-Katz technique is widely used for the diagnosis of soil-transmitted helminthiasis in epidemiological surveys and is believed to be an inexpensive method. The FLOTAC tech
Geostatistical model-based estimates of schistosomiasis prevalence among individuals aged </=20 years in West Africa (Publications)
BACKGROUND: Schistosomiasis is a water-based disease that is believed to affect over 200 million people with an estimated 97% of the infections concentrated in Africa. However, these statistics are la
Low efficacy of single-dose albendazole and mebendazole against hookworm and effect on concomitant helminth infection in Lao PDR (Publications)
BACKGROUND: Albendazole and mebendazole are increasingly deployed for preventive chemotherapy targeting soil-transmitted helminth (STH) infections. We assessed the efficacy of single oral doses of alb