Identification and characterization of FTY720 for the treatment of human African trypanosomiasis (Publications)
Screening of a focused library identified FTY720 (Fingolimod, Gilenya(R)) as a potent, selective anti-trypanosomal compound active against T.b. gambiense and T.b. rhodesiense, the causative agents of
Comparison for the effects of different components of temperature variability on mortality: A multi-country time-series study (Publications)
Background Temperature variability (TV) is associated with increased mortality risk. However, it is still unknown whether intra-day or inter-day TV has different effects. Objectives We aimed to assess
Randomized trial to improve children's body composition and micronutrient status among South African Children (Publications)
INTRODUCTION: Physical activity (PA) promotion combined with multi-micronutrient supplementation (MMNS) among school-age children may reduce fat mass accrual and increase muscle mass through different
Comparison for the effects of different components of temperature variability on mortality: a multi-country time-series study (Publications)
BACKGROUND: Temperature variability (TV) is associated with increased mortality risk. However, it is still unknown whether intra-day or inter-day TV has different effects. OBJECTIVES: We aimed to asse
Health policy analysis to continuously improve and streamline services for the management and coordination of care of individuals (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/health-policy-analysis-to-continuously-improve-and-streamline-services-for-the-management-and-coordination-of-care-of-individuals
This research project embarks on a comprehensive analysis of the implementation of Physical Activity Level (PAL) programs across various countries, focusing on the determinants of success and failure.
Investigations of the metabolites of the trypanocidal drug melarsoprol (Publications)
BACKGROUND: Melarsoprol remains the first-choice drug for trypanosomiasis (human African sleeping sickness). To contribute to the sparse pharmacologic data and to better understand the cause of the fr
Swiss TPH: 30 years of R&D towards new drugs for tropical diseases (Publications)
The year 2023 marks the 80th anniversary of the Swiss Tropical and Public Health Institute (Swiss TPH). Associated with the University of Basel, Swiss TPH combines research, education and services, wo
Effectiveness and acceptance of group therapy as a mental health intervention for people living with HIV in Africa - a scoping literature review (Publications)
Mental health problems are highly prevalent among people living with HIV/AIDS (PLWHA), yet mental health care in African countries is scarce. There is growing interest in understanding the effect of g