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1. Structure-activity-relationship studies around the 2-amino group and pyridine core of antimalarial 3,5-diarylaminopyridines lead to a novel series of... (Publications)

   Structure-activity-relationship studies around the 2-amino group and pyridine core of antimalarial 3,5-diarylaminopyridines lead to a novel series of pyrazine analogues with oral in vivo activity

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   Replacement of the pyridine core of antimalarial 3,5-diaryl-2-aminopyridines led to the identification of a novel series of pyrazine analogues with potent oral antimalarial activity. However, other ch

2. Toward the development of dual-targeted glyceraldehyde-3-phosphate dehydrogenase/trypanothione reductase inhibitors against <em>Trypanosoma... (Publications)

   Toward the development of dual-targeted glyceraldehyde-3-phosphate dehydrogenase/trypanothione reductase inhibitors against <em>Trypanosoma brucei</em> and <em>Trypanosoma cruzi</em>

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   A significant improvement in the treatment of trypanosomiases has been achieved with the recent development of nifurtimox-eflornithine combination therapy (NECT). As an alternative to drug combination

3. Deciphering the origin of dengue virus introduced in Madeira, Portugal (Publications)

   Deciphering the origin of dengue virus introduced in Madeira, Portugal

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4. Investigation of acyclic uridine amide and 5'-amido nucleoside analogues as potential inhibitors of the <em>Plasmodium falciparum</em> dUTPase (Publications)

   Investigation of acyclic uridine amide and 5'-amido nucleoside analogues as potential inhibitors of the <em>Plasmodium falciparum</em> dUTPase

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   Previously we have shown that trityl and diphenyl deoxyuridine derivatives and their acyclic analogues can inhibit Plasmodium falciparum dUTPase (PfdUTPase). We report the synthesis of conformationall

5. Comparison of performance of land use regression models derived for Catalunya, Spain (Publications)

   Comparison of performance of land use regression models derived for Catalunya, Spain

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6. Differential virulence and disease progression following <em>Mycobacterium tuberculosis</em> complex infection of the common marmoset (<em>Callithrix... (Publications)

   Differential virulence and disease progression following <em>Mycobacterium tuberculosis</em> complex infection of the common marmoset (<em>Callithrix jacchus</em>)

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   Existing small-animal models of tuberculosis (TB) rarely develop cavitary disease, limiting their value for assessing the biology and dynamics of this highly important feature of human disease. To dev

7. Signifikant kürzere Anästhesiezeit bei lumbaler Wirbelsäulenchirurgie: prozessanalytischer Vergleich von Spinalanästhesie und Intubationsnarkose (Publications)

   Signifikant kürzere Anästhesiezeit bei lumbaler Wirbelsäulenchirurgie: prozessanalytischer Vergleich von Spinalanästhesie und Intubationsnarkose

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   INTRODUCTION: Most surgery of the lumbar spine is performed with the patient under general anesthesia (GA); however, qualitative benefits of spinal anesthesia (SA) have been reported. The goal of this

8. Human and animal health in nomadic communities of Chad: zoonoses, morbidity and health services (Publications)

   Human and animal health in nomadic communities of Chad: zoonoses, morbidity and health services

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9. Clinical aspects and management of cutaneous leishmaniasis in rheumatoid patients treated with TNF-a antagonists (Publications)

   Clinical aspects and management of cutaneous leishmaniasis in rheumatoid patients treated with TNF-a antagonists

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   Patients under immunosuppressive therapy with tumor necrosis factor alpha (TNF-?) antagonists are vulnerable to various opportunistic infections including leishmaniasis. We present a case series of 8

10. Indian contribution to the cultural formulation interview and the DSM-5: missing details from the position paper [Letter to the editor] (Publications)

    Indian contribution to the cultural formulation interview and the DSM-5: missing details from the position paper [Letter to the editor]

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