Animal-assisted psychotherapy for pediatric chronic pain: case series of an open pilot study to test initial feasibility and potential efficacy (Publications)
To date, however, AAIs have not been examined in pediatric chronic pain. METHODS: The aim of this open pilot study was to examine the initial feasibility of recruitment and potential efficacy of an an [...] revealed that patients and their parents had a positive attitude towards AAIs. CONCLUSION: Our initial open pilot study is the first to investigate AAIs in the context of pediatric chronic pain. Notably, we
Ultrasononography in managing extrapulmonary tuberculosis: a randomized, controlled, parallel, superiority, open-label trial (Publications)
BACKGROUND: Patients with suspected extrapulmonary tuberculosis are often treated empirically. We hypothesized that extended focused assessment with sonography for human immunodeficiency virus (HIV) a
Post-exposure lopinavir-ritonavir prophylaxis versus surveillance for individuals exposed to SARS-CoV-2: the COPEP pragmatic open-label, cluster... (Publications)
(LPV/r) was repurposed as a potential PEP agent against COVID-19. Methods: We conducted a pragmatic open-label, parallel, cluster-randomised superiority trial in four sites in Switzerland and Brazil between
Discovery of novel antischistosomal scaffolds from the open access Pandemic Response Box (Publications)
prevent the emergence of resistance. METHODS: We screened 400 drug-like compounds contained in the open-access Pandemic Response Box (PRB) against newly transformed schistosomula (NTS) at a concentration
Screening open access compound libraries and repurposing drugs to identify and characterize new molecules active against schistosomiasis and other... (Publications)
hic early drug development with a strong emphasis on schistosomiasis. Activity-based screening of open access libraries has identified new potent antischistosomal molecules. Investigating the activity [...] that could be used for further compound development. Finally, this work highlights the importance of open access libraries, drug repurposing and non-profit product development partnerships to stimulate the
Safety and efficacy of oral fexinidazole in children with <em>gambiense </em>human African trypanosomiasis: a multicentre, single-arm, open-label,... (Publications)
disease stages of gambiense human African trypanosomiasis. METHODS: We did a multicentre, single-arm, open-label, phase 2-3 trial at eight district hospitals in the Democratic Republic of the Congo. We recruited
Less is more: repellent-treated fabric strips as a substitute for full screening of open eave gaps for indoor and outdoor protection from malaria... (Publications)
at comparing the protection provided by transfluthrin-treated and untreated complete screens over open eave gaps with incomplete transfluthrin-treated eave strips as a potential replacement for a full [...] finding a human volunteer indoors and attempting to bite were similar whether the eaves were completely open or there was an untreated fabric strip fixed around the eaves. However, when the eave gap was completely