Professor Melissa Penny, PhD, PD

Golumbeanu M, Yang G.J, Camponovo F, Stuckey E.M, Hamon N, Mondy M, Rees S, Chitnis N, Cameron E, Penny M.A. Leveraging mathematical models of disease dynamics and machine learning to improve development of novel malaria interventions. Infect Dis Poverty. 2022;11:61. DOI: 10.1186/s40249-022-00981-1

Kelly S.L, Le Rütte E.A, Richter M, Penny M.A, Shattock A.J. COVID-19 vaccine booster strategies in light of emerging viral variants: frequency, timing, and target groups. Infect Dis Ther. 2022;11(5):2045-2061. DOI: 10.1007/s40121-022-00683-z

Le Rütte E.A, Shattock A.J, Chitnis N, Kelly S.L, Penny M.A. Modelling the impact of Omicron and emerging variants on SARS-CoV-2 transmission and public health burden. Commun Med (Lond). 2022;2:93. DOI: 10.1038/s43856-022-00154-z

Masserey T, Lee T, Golumbeanu M, Shattock A.J, Kelly S.L, Hastings I.M, Penny M.A. The influence of biological, epidemiological, and treatment factors on the establishment and spread of drug-resistant Plasmodium falciparum. Elife. 2022;11:e7763. DOI: 10.7554/eLife.77634

Nekkab N, Penny M.A. Accelerated development of malaria monoclonal antibodies. Cell Rep Med. 2022;3(10):100786. DOI: 10.1016/j.xcrm.2022.100786

Shattock A.J, Le Rütte E.A, Dünner R.P, Sen S, Kelly S.L, Chitnis N, Penny M.A. Impact of vaccination and non-pharmaceutical interventions on SARS-CoV-2 dynamics in Switzerland. Epidemics. 2022;38:100535. DOI: 10.1016/j.epidem.2021.100535

Watson O.J, Gao B, Nguyen T.D, Tran T.N, Penny M.A, Smith D.L, Okell L, Aguas R, Boni M.F. Pre-existing partner-drug resistance to artemisinin combination therapies facilitates the emergence and spread of artemisinin resistance: a consensus modelling study. Lancet Microbe. 2022;3(9):e701–e710. DOI: 10.1016/S2666-5247(22)00155-0

Yang G.J, Shang L.Y, Zhou X.N, Lee T.E, Bi B, White M, Smith T.A, Penny M.A. The empirical support for the radical cure strategy for eliminating Plasmodium vivax in China. BMC Med. 2022;20:17. DOI: 10.1186/s12916-021-02214-y

Burgert L, Zaloumis S, Dini S, Marquart L, Cao P, Cherkaoui M, Gobeau N, McCarthy J, Simpson J.A, Möhrle J.J, Penny M.A. Parasite-host dynamics throughout antimalarial drug development stages complicate the translation of parasite clearance. Antimicrob Agents Chemother. 2021;65(4):e01539-20. DOI: 10.1128/AAC.01539-20

Camponovo F, Lee T.E, Russell J.R, Burgert L, Gerardin J, Penny M.A. Mechanistic within-host models of the asexual Plasmodium falciparum infection: a review and analytical assessment. Malar J. 2021;20:309. DOI: 10.1186/s12936-021-03813-z

Galactionova K, Smith T.A, Penny M.A. Insights from modelling malaria vaccines for policy decisions: the focus on RTS,S. Malar J. 2021;20:439. DOI: 10.1186/s12936-021-03973-y

Reiker T, Golumbeanu M, Shattock A, Burgert L, Smith T.A, Filippi S, Cameron E, Penny M.A. Emulator-based Bayesian optimization for efficient multi-objective calibration of an individual-based model of malaria. Nat Commun. 2021;12:7212. DOI: 10.1038/s41467-021-27486-z

Stader F, Courlet P, Kinvig H, Penny M.A, Decosterd L.A, Battegay M, Siccardi M, Marzolini C. Clinical data combined with modelling and simulation indicate unchanged drug-drug interaction magnitudes in the elderly. Clin Pharmacol Ther. 2021;109(2):471-484. DOI: 10.1002/cpt.2017

Burgert L, Rottmann M, Wittlin S, Gobeau N, Krause A, Dingemanse J, Möhrle J.J, Penny M.A. Ensemble modeling highlights importance of understanding parasite-host behavior in preclinical antimalarial drug development. Sci Rep. 2020;10:4410. DOI: 10.1038/s41598-020-61304-8

Camponovo F, Campo J.J, Le T.Q, Oberai A, Hung C, Pablo J.V, Teng A.A, Liang X, Sim B.K.L, Jongo S, Abdulla S, Tanner M, Hoffman S.L, Daubenberger C, Penny M. Proteome-wide analysis of a malaria vaccine study reveals personalized humoral immune profiles in Tanzanian adults. Elife. 2020;9:e53080. DOI: 10.7554/eLife.53080

Galactionova K, Velarde M, Silumbe K, Miller J, McDonnell A, Aguas R, Smith T.A, Penny M.A. Costing malaria interventions from pilots to elimination programmes. Malar J. 2020;19:332. DOI: 10.1186/s12936-020-03405-3

Penny M.A, Camponovo F, Chitnis N, Smith T.A, Tanner M. Future use-cases of vaccines in malaria control and elimination. Parasite Epidemiol Control. 2020;10:e00145. DOI: 10.1016/j.parepi.2020.e00145

Smith T, Maire N, Ross A, Penny M, Chitnis N, Schapira A, Studer A, Genton B, Lengeler C, Tediosi F, de Savigny D, Tanner M. Towards a comprehensive simulation model of malaria epidemiology and control. Parasitology. 2008;135(13):1507-1516