Group | Clinical Epidemiology
Projects to improve the quality of health care for children
The PeDiAtrick project aims to improve the quality of health care for children through the use of an electronic decision support system that promotes evidence-based medicine and rational use of drugs. It builds on the Integrated Management of Childhood Illness (IMCI) flowchart and on findings from the IMALDIA aetiology study, which identified predictors of mild and severe disease.
In tropical primary care facilities, fever is one of the most frequent complaint presented by patients. With the global decline in malaria transmission and emergence of viral epidemics, more attention has been recently given to non-malaria causes of febrile episodes. Health workers urgently need novel diagnostic tools and evidence-based guidelines to better manage febrile patients in an integrated way. The goal is to improve clinical outcome through targeted appropriate treatment, but also decrease unnecessary antimicrobial use to mitigate resistance.
The ALIVE project assesses the impact of artemether/lumefantrine (ALu) introduction as first-line treatment on malaria transmission and child mortality in two rural districts of Tanzania. Both transmission and mortality rates declined significantly during the first three years of ALu implementation and compliance was found to be excellent.