The research group Disease and Intervention Dynamics focuses on developing and using mathematical models to understand parasite, host and intervention dynamics. The main aim is to generate evidence for decision-making along the whole pathway of new tool development, from preclinical to clinical testing, and at implementation in real populations and health systems. The model-based evidences ensure efficient selection of optimal drugs and vaccines to achieve disease burden reduction and elimination.
Our Main Emphasis
In particular, we investigate pharmacokinetic and pharmacodynamics at pre-clinical and clinical level for new drugs to treat malaria and helminths. We collaborate with the University Hospital Basel on understanding drug-drug interactions for HIV drugs. We assess new malaria vaccines at clinical and implementation level. And we use data and models to explore most effective, cost-effective and equitable delivery of current and new malaria interventions.