Project

CoDuBu - Co-occurrence of common chronic infections and common non-communicable diseasess in rural and urben C

The co-occurrence of infectious diseases (IDs) and non-communicable diseases (NCDs) at the level of individuals is poorly studied, despite the fact that this dual burden has become a reality for many low- and middle-income countries (LMIC). Even for highly prevalent IDs (e.g. helminthiases and malaria) and NCDs (e.g. hypertension and diabetes) very little is known about how they influence each other. Health and demographic surveillance systems (HDSS) are recognised as powerful platforms for assessment and longitudinal monitoring of key demographic parameters (e.g. pregnancy, birth, migration, death) and health indicators (e.g. causes of death and burden of disease). HDSS provides a unique means for population-based epidemiological and health systems research to take place. As there is a substantial lack of population-based evidence on the co-occurrence and mutual influence of highly prevalent chronic and sub chronic helminth infections and malaria in sub-Saharan Africa with increasingly prevalent NCDs (e.g. hypertension and diabetes), the Taabo HDSS in south-central Côte d’Ivoire with a combination of an urban and a rural part has a unique research advantage to narrowing this gap.

Goal: To deepen our understanding of the dual burden of common IDs (helminthiases and malaria) and common NCDs (hypertension and diabetes) among adults in the Taabo HDSS in south-central Côte d’Ivoire. Understanding the co-occurrence of IDs and NCDs is of relevance to:

     

  • innovative dual burden of disease management in a typical West African setting;
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  • initiate primary prevention programmes in a typical West African setting; and
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  • deepen mechanistic disease understanding for novel screening, diagnostic and drug targets for improved burden of disease estimation.
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The proposed project will be implemented in the Taabo HDSS, located 160 km north-west of Abidjan, the economic capital of Côte d'Ivoire. Taabo is situated in the health district of Tiassalé with an estimated population size of 200,000 people.

Phase I: Study protocol, standard operating procedures, ethical approval and preparation of field work (Months 1-5)
Phase II: Conduct of field work (Months 6-10)
Phase III: Data analysis and reporting (Months 11 and 12)

Implementing Partners: The project will be directed and supervised by a Scientific Steering Committee. The implementation of the current project will be undertaken by the Centre Suisse de Recherches Scientifiques en Côte d’Ivoire (CSRS) in collaboration with Swiss TPH Technical and administrative support will be provided by Swiss TPH. Scientific and technical support will be provided by the Université Félix Houphouët-Boigny, the Institut Nationale de Santé Publique (INSP) and other partner institutions in Côte d’Ivoire.

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Selected projects at this location:

Involved Regions: Africa
Involved Countries: Côte d'Ivoire

Contact

Nicole Probst-Hensch

Nicole Probst-Hensch, Professor, PhD (Pharmacy and Epidemiology), MPH
Head of Department, Group Leader, Head of Unit

+41612848378
nicole.probstswisstph.ch

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