MMC elimination costing

The project will generate evidence on the trade-offs between cost and effectiveness of malaria elimination interventions. This includes surveillance and a range of targeted and focal malaria elimination interventions when added incrementally to current levels of routine malaria control and case...

Ongoing
01.12.2017 - 31.10.2020
Research project
Disease and Intervention Dynamics
Melissa Penny
Further development of simulations of Plasmodium falciparum interventions and their integration with the needs of stakeholders II

This project supports the development and use of mathematical models for predicting the effects of different malaria interventions.  It is centered on contributions to the multi-group Bill and Melinda Gates Foundation Malaria Modeling Consortium (MMC). Specific areas additional to the MMC...

Ongoing
16.05.2016 - 30.04.2021
Research project
Infectious Disease Modelling, Epidemiology and Transmission Dynamics
Thomas Smith
Design of trials for pathogen elimination

In field trials of new interventions against mosquitoes and the diseases they transmit, there are often spill-over effects between areas that receive the intervention and others that do not, because of mosquito movement.  This project is developing ways of designing trials to make best use of data...

Ongoing
01.01.2016 - 31.12.2018
Research project
RGS Effective coverage - Impact of systems failures in malaria service delivery in Africa

Malaria treatment provides individual benefits by curing infection and preventing progression to severe disease. Treatment also provides community-level benefits by reducing the infectious reservoir. However, across endemic countries treatment does not always lead to a complete parasitological cure,...

Ongoing
01.01.2016 - 31.12.2018
Research project
Infectious Disease Modelling, Disease and Intervention Dynamics
Melissa Penny
SNIS Mosquito Susceptibility - Increased susceptibility to Plasmodium falciparum of insecticide resistant Anopheles in West Africa

This project aims to assess how widespread the susceptibility to Plasmodium of insecticide-resistant Anopheles is, and to assess the risk associated with this phenomenon in relationship with human behavioural changes regarding their use of bed nets and insecticides.

Ongoing
01.10.2015 - 30.09.2017
Research project
FIVC - Operational Framework for Integrated Vector Control

Aims
Our goal is to develop strategies for the integrated management of vectors transmitting malaria and other major vector borne for decision making at the country level.

Methods
We propose to develop country-level maps illustrating the distribution of vector-borne diseases (VBDs) and carry out two...

Ongoing
14.11.2012 - 31.07.2016
Research project
Ongoing
01.02.2012 - 31.12.2015
Clinical Trial
Further development of simulations of Plasmodium falciparum interventions and their integration with the needs of stakeholders

Background
We have developed a general computing platform for comparing, fitting, and evaluating different individual-based stochastic simulations of malaria epidemiology.

Aims
In the next phase of the project, we propose to exploit the functionality of this modeling platform to provide high quality...

Ongoing
01.05.2011 - 31.03.2016
Research project
Infectious Disease Modelling
Thomas Smith
PATH - PATH - MVI Malaria Vaccine Modeling: Service Agreement

Swiss TPH is carrying out simulations of the public health impact of the RTS,S malaria vaccine, with the support of PATH-MVI. The work involves simulation of the impact of adding vaccines in the context of improved control, considering various vaccine profiles and deployment strategies. The work...

Ongoing
01.11.2009 - 31.12.2017
Research project
PATH Malaria Vaccine Initiative (MVI)
Infectious Disease Modelling, Disease and Intervention Dynamics
Melissa Penny