Arbués A, Brees D, Chibout S.D, Fox T, Kammüller M, Portevin D. TNF-α antagonists differentially induce TGF-β1-dependent resuscitation of dormant-like Mycobacterium tuberculosis. PLoS Pathog. 2020;16(2):e1008312. DOI: 10.1371/journal.ppat.1008312

2020
Journal Article
PubMed (32069329)
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Arbués A, Kammüller M, Portevin D. Generating three-dimensional human granulomas in vitro to study Mycobacterium tuberculosis-host interaction. Bio Protoc. 2020;10(22):e3820. DOI: 10.21769/BioProtoc.3820

2020
Journal Article

Amelio P, Portevin D, Hella J, Reither K, Kamwela L, Lweno O, Tumbo A, Geoffrey L, Ohmiti K, Ding S, Pantaleo G, Daubenberger C, Perreau M. HIV infection functionally impairs Mycobacterium tuberculosis-specific CD4 and CD8 T-cell responses. J Virol. 2019;93(5):e01728-18. DOI: 10.1128/JVI.01728-18

2019
Journal Article
PubMed (30541853)
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Steiner-Monard V, Kamaka K, Karoui O, Roethlisberger S, Audran R, Daubenberger C, Fayet-Mello A, Erdmann-Voisin A, Felger I, Geiger K, Govender L, Houard S, Huber E, Mayor C, Mkindi C, Portevin D, Rusch S, Schmidlin S, Tiendrebeogo R.W, Theisen M, Thierry A.C, Vallotton L, Corradin G, Leroy O, Abdulla S, Shekalaghe S, Genton B, Spertini F, Jongo S.A. The candidate blood-stage malaria vaccine P27A induces a robust humoral response in a fast track to the field phase I trial in exposed and non exposed volunteers. Clin Infect Dis. 2019;68(3):466-474. DOI: 10.1093/cid/ciy514

2019
Journal Article
PubMed (29945169)

Boillat-Blanco N, Tumbo A.N, Perreau M, Amelio P, Ramaiya K.L, Mganga M, Schindler C, Gagneux S, Reither K, Probst-Hensch N, Pantaleo G, Daubenberger C, Portevin D. Hyperglycaemia is inversely correlated with live M. bovis BCG-specific CD4+ T cell responses in Tanzanian adults with latent or active tuberculosis. Immun Inflamm Dis. 2018;6(2):345-353. DOI: 10.1002/iid3.222

2018
Journal Article
PubMed (29642283)
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Vogel G, Cuénod A, Mouchet R, Strauss A, Daubenberger C, Pflueger V, Portevin D. Functional characterization and phenotypic monitoring of human hematopoietic stem cell expansion and differentiation of monocytes and macrophages by whole-cell mass spectrometry. Stem Cell Res. 2018;26:47-54. DOI: 10.1016/j.scr.2017.11.013

2018
Journal Article
PubMed (29227832)
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Amelio P, Portevin D, Reither K, Mhimbira F, Mpina M, Tumbo A, Nickel B, Marti H, Knopp S, Ding S, Penn-Nicholson A, Darboe F, Ohmiti K, Scriba T.J, Pantaleo G, Daubenberger C, Perreau M. Mixed Th1 and Th2 Mycobacterium tuberculosis-specific CD4 T cell responses in patients with active pulmonary tuberculosis from Tanzania. PLoS Negl Trop Dis. 2017;11(7):e0005817. DOI: 10.1371/journal.pntd.0005817

2017
Journal Article
PubMed (28759590)
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Portevin D, Moukambi F, Mpina M, Bauer A, Haraka F, Chachage M, Metzger P, Saathoff E, Clowes P, Ntinginya N.E, Rachow A, Hoelscher M, Reither K, Daubenberger C.A, Geldmacher C. Maturation and mip-1beta production of cytomegalovirus-specific T cell responses in Tanzanian children, adolescents and adults: impact by HIV and Mycobacterium tuberculosis co-infections. PLoS One. 2015;10(5):e0126716. DOI: 10.1371/journal.pone.0126716

2015
Journal Article
PubMed (25974183)
Link

Portevin D, Pflüger V, Otieno P, Brunisholz R, Vogel G, Daubenberger C. Quantitative whole-cell MALDI-TOF MS fingerprints distinguishes human monocyte sub-populations activated by distinct microbial ligands. BMC Biotechnol. 2015;15:24. DOI: 10.1186/s12896-015-0140-1

2015
Journal Article
PubMed (25887592)
Link

Portevin D, Moukambi F, Clowes P, Bauer A, Chachage M, Ntinginya E.N, Mfinanga E, Said K, Haraka F, Rachow A, Saathoff E, Mpina M, Jugheli L, Lwilla F, Marais B.J, Hoelscher M, Daubenberger C, Reither K, Geldmacher C. Assessment of the novel T-cell activation marker-tuberculosis assay for diagnosis of active tuberculosis in children: a prospective proof-of-concept study. Lancet Infect Dis. 2014;14(10):931-938. DOI: 10.1016/S1473-3099(14)70884-9

2014
Journal Article
PubMed (25185458)

Portevin D, Sukumar S, Coscolla M, Shui G, Li B, Guan X.L, Bendt A.K, Young D, Gagneux S, Wenk M.R. Lipidomics and genomics of Mycobacterium tuberculosis reveal lineage-specific trends in mycolic acid biosynthesis. Microbiologyopen. 2014;3(6):823-835. DOI: 10.1002/mbo3.193

2014
Journal Article
PubMed (25238051)

Portevin D, Young D. Natural killer cell cytokine response to M. bovis BCG is associated with inhibited proliferation, increased apoptosis and ultimate depletion of NKp44(+)CD56(bright) cells. PLoS One. 2013;8(7):e68864. DOI: 10.1371/journal.pone.0068864

2013
Journal Article
PubMed (23874793)
Link

Via L.E, Weiner D.M, Schimel D, Lin P.L, Dayao E, Tankersley S.L, Cai Y, Coleman M.T, Tomko J, Paripati P, Orandle M, Kastenmayer R.J, Tartakovsky M, Rosenthal A, Portevin D, Eum S.Y, Lahouar S, Gagneux S, Young D.B, Flynn J.L, Barry III C.E. Differential virulence and disease progression following Mycobacterium tuberculosis complex infection of the common marmoset (Callithrix jacchus). Infect Immun. 2013;81(8):2909-2919. DOI: 10.1128/IAI.00632-13

2013
Journal Article
PubMed (23716617)

Portevin D, Gagneux S, Comas I, Young D. Human macrophage responses to clinical isolates from the Mycobacterium tuberculosis complex discriminate between ancient and modern lineages. PLoS Pathog. 2011;7(3):e1001307. DOI: 10.1371/journal.ppat.1001307

2011
Journal Article
PubMed (21408618)
Link