Abidi S.K, Harris M, Muyoyeta M, Dheda K, Esmail A, Reither K, Breuninger M, Qi A, Denkinger C, Korobitsyn A, Pai M, Benedetti A, Khan F.A. An individual patient data meta-analysis to estimate the diagnostic accuracy of a machine learning-based software for analyzing chest x-rays of persons with symptoms of pulmonary tuberculosis: preliminary findings. Am J Respir Crit Care Med, 2019;199:A5167

2019
Conference Paper

Amelio P, Portevin D, Hella J, Reither K, Kamwela L, Lweno O, Tumbo A, Geoffrey L, Ohmiti K, Ding S, Pantaleo G, Daubenberger C, Perreau M. HIV infection functionally impairs Mycobacterium tuberculosis-specific CD4 and CD8 T-cell responses. J Virol. 2019;93(5):e01728-18. DOI: 10.1128/JVI.01728-18

2019
Journal Article
PubMed (30541853)
Link

Mhalu G, Hella J, Mhimbira F, Said K, Mosabi T, Mlacha Y.P, Schindler C, Gagneux S, Reither K, de Hoogh K, Weiss M.G, Zemp E, Fenner L. Pathways and associated costs of care in patients with confirmed and presumptive tuberculosis in Tanzania: a cross-sectional study. BMJ Open. 2019;9(4):e025079. DOI: 10.1136/bmjopen-2018-025079

2019
Journal Article
PubMed (31005914)
Link

Mhalu G, Weiss M.G, Hella J, Mhimbira F, Mahongo E, Schindler C, Reither K, Fenner L, Zemp E, Merten S. Explaining patient delay in healthcare seeking and loss to diagnostic follow-up among patients with presumptive tuberculosis in Tanzania: a mixed-methods study. BMC Health Serv Res. 2019;19:217. DOI: 10.1186/s12913-019-4030-4

2019
Journal Article
PubMed (30953502)
Link

Mhimbira F, Hiza H, Mbuba E, Hella J, Kamwela L, Sasamalo M, Ticlla M, Said K, Mhalu G, Chiryamkubi M, Schindler C, Reither K, Gagneux S, Fenner L. Prevalence and clinical significance of respiratory viruses and bacteria detected in tuberculosis patients compared to household contact controls in Tanzania: a cohort study. Clin Microbiol Infect. 2019;25(1):107 e1-107 e7. DOI: 10.1016/j.cmi.2018.03.019

2019
Journal Article
PubMed (29581053)

Nathavitharana R.R, Yoon C, Macpherson P, Dowdy D.W, Cattamanchi A, Somoskovi A, Broger T, Ottenhoff T.H.M, Arinaminpathy N, Lonnroth K, Reither K, Cobelens F, Gilpin C, Denkinger C.M, Schumacher S.G. Guidance for studies evaluating the accuracy of tuberculosis triage tests. J Infect Dis. 2019;220(Suppl. 3):S116-S125. DOI: 10.1093/infdis/jiz243

2019
Journal Article
PubMed (31593600)

Ndege R, Weisser M, Elzi L, Diggelmann F, Bani F, Gingo W, Sikalengo G, Mapesi H, McHomvu E, Kamwela L, Mnzava D, Battegay M, Reither K, Paris D.H, Rohacek M. Sonography to rule out tuberculosis in sub-Saharan Africa: a prospective observational study. Open Forum Infect Dis. 2019;6(4):ofz154. DOI: 10.1093/ofid/ofz154

2019
Journal Article
PubMed (31041350)
Link

Nooh F, Crump L, Hashi A, Tschopp R, Schelling E, Reither K, Hattendorf J, Ali S.M, Obrist B, Utzinger J, Zinsstag J. The impact of pastoralist mobility on tuberculosis control in Ethiopia: a systematic review and meta-synthesis. Infect Dis Poverty. 2019;8:73. DOI: 10.1186/s40249-019-0583-z

2019
Journal Article
PubMed (31474228)
Link

Rutaihwa L, Menardo F, Stucki D, Gygli S.M, Ley S.D, Malla B, Feldmann J, Borrell S, Beisel C, Middelkoop K, Carter J.E, Diero L, Ballif M, Jugheli L, Reither K, Fenner L, Brites D, Gagneux S. Multiple introductions of Mycobacterium tuberculosis lineage 2-Beijing into Africa over centuries. Front Ecol Evol. 2019;7:112. DOI: 10.3389/fevo.2019.00112

2019
Journal Article
Link

Rutaihwa L.K, Sasamalo M, Jaleco A, Hella J, Kingazi A, Kamwela L, Kingalu A, Malewo B, Shirima R, Doetsch A, Feldmann J, Reinhard M, Borrell S, Brites D, Reither K, Doulla B, Fenner L, Gagneux S. Insights into the genetic diversity of Mycobacterium tuberculosis in Tanzania. PLoS One. 2019;14(4):e0206334. DOI: 10.1371/journal.pone.0206334

2019
Journal Article
PubMed (30978186)
Link

Santos V.S, Goletti D, Kontogianni K, Adams E.R, Molina-Moya B, Dominguez J, Crudu V, Martins-Filho P.R.S, Ruhwald M, Lawson L, Bimba J.S, Garcia-Bastero A.L, Petrone L, Kabeer B.S, Reither K, Cuevas L.E. Acute phase proteins and IP-10 as triage tests for the diagnosis of tuberculosis: a systematic review and meta-analysis. Clin Microbiol Infect. 2019;25(2):169-177. DOI: 10.1016/j.cmi.2018.07.017

2019
Journal Article
PubMed (30076971)
Link

Boillat-Blanco N, Tumbo A.N, Perreau M, Amelio P, Ramaiya K.L, Mganga M, Schindler C, Gagneux S, Reither K, Probst-Hensch N, Pantaleo G, Daubenberger C, Portevin D. Hyperglycaemia is inversely correlated with live M. bovis BCG-specific CD4+ T cell responses in Tanzanian adults with latent or active tuberculosis. Immun Inflamm Dis. 2018;6(2):345-353. DOI: 10.1002/iid3.222

2018
Journal Article
PubMed (29642283)
Link

Haraka F, Nathavitharana R.R, Schumacher S.G, Kakolwa M, Denkinger C.M, Gagneux S, Reither K, Ross A. Impact of diagnostic test Xpert MTB/RIF® on health outcomes for tuberculosis. Cochrane Database Syst Rev. 2018(in press). DOI: 10.1002/14651858.CD012972

2018
Journal Article

Hella J, Cercamondi C.I, Mhimbira F, Sasamalo M, Stoffel N, Zwahlen M, Bodmer T, Gagneux S, Reither K, Zimmermann M.B, Risch L, Fenner L. Anemia in tuberculosis cases and household controls from Tanzania: contribution of disease, coinfections, and the role of hepcidin. PLoS One. 2018;13(4):e0195985. DOI: 10.1371/journal.pone.0195985

2018
Journal Article
PubMed (29677205)
Link

Hodel N.C, Hamad A, Praehauser C, Mwangoka G, Kasella I.M, Reither K, Abdulla S, Hatz C.F.R, Mayr M. The epidemiology of chronic kidney disease and the association with non-communicable and communicable disorders in a population of sub-Saharan Africa. PLoS One. 2018;13(10):e0205326. DOI: 10.1371/journal.pone.0205326

2018
Journal Article
PubMed (30379902)
Link

Sabi I, Rachow A, Mapamba D, Clowes P, Ntinginya N.E, Sasamalo M, Kamwela L, Haraka F, Hoelscher M, Paris D.H, Saathoff E, Reither K. Xpert MTB/RIF Ultra assay for the diagnosis of pulmonary tuberculosis in children: a multicentre comparative accuracy study. J Infect. 2018;77(4):321-327. DOI: 10.1016/j.jinf.2018.07.002

2018
Journal Article
PubMed (30036606)

Sikalengo G, Hella J, Mhimbira F, Rutaihwa L.K, Bani F, Ndege R, Sasamalo M, Kamwela L, Said K, Mhalu G, Mlacha Y, Hatz C, Knopp S, Gagneux S, Reither K, Utzinger J, Tanner M, Letang E, Weisser M, Fenner L. Distinct clinical characteristics and helminth co-infections in adult tuberculosis patients from urban compared to rural Tanzania. Infect Dis Poverty. 2018;7:24. DOI: 10.1186/s40249-018-0404-9

2018
Journal Article
PubMed (29580279)
Link

Zoller T, Mfinanga E.H, Zumba T.B, Asilia P.J, Mutabazi E.M, Wimmersberger D, Kurth F, Mhimbira F, Haraka F, Reither K. Chronic airflow obstruction in Tanzania - a cross-sectional study. BMC Pulm Med. 2018;18(1):11. DOI: 10.1186/s12890-018-0577-9

2018
Journal Article
PubMed (29351754)
Link

Aarnoutse R.E, Kibiki G.S, Reither K, Semvua H.H, Haraka F, Mtabho C.M, Mpagama S.G, van den Boogaard J, Sumari-de Boer I.M, Magis-Escurra C, Wattenberg M, Logger J.G.M, Te Brake L.H.M, Hoelscher M, Gillespie S.H, Colbers A, Phillips P.P.J, Plemper van Balen G, Boeree M.J, Pan Acea Consortium. Pharmacokinetics, tolerability, and bacteriological response of rifampin administered at 600, 900, and 1,200 milligrams daily in patients with pulmonary tuberculosis. Antimicrob Agents Chemother. 2017;61(11):e01054-17. DOI: 10.1128/AAC.01054-17

2017
Journal Article
PubMed (28827417)

Amelio P, Portevin D, Reither K, Mhimbira F, Mpina M, Tumbo A, Nickel B, Marti H, Knopp S, Ding S, Penn-Nicholson A, Darboe F, Ohmiti K, Scriba T.J, Pantaleo G, Daubenberger C, Perreau M. Mixed Th1 and Th2 Mycobacterium tuberculosis-specific CD4 T cell responses in patients with active pulmonary tuberculosis from Tanzania. PLoS Negl Trop Dis. 2017;11(7):e0005817. DOI: 10.1371/journal.pntd.0005817

2017
Journal Article
PubMed (28759590)
Link

Boeree M.J, Heinrich N, Aarnoutse R, Diacon A.H, Dawson R, Rehal S, Kibiki G.S, Churchyard G, Sanne I, Ntinginya N.E, Minja L.T, Hunt R.D, Charalambous S, Hanekom M, Semvua H, Mpagama S.G, Manyama C, Mtafya B, Reither K, Wallis R.S, Venter A, Narunsky K, Mekota A, Henne S, Colbers A, van Balen G.P, Gillespie S.H, Phillips P.P.J, Hoelscher M. High-dose rifampicin, moxifloxacin, and SQ109 for treating tuberculosis: a multi-arm, multi-stage randomised controlled trial. Lancet Infect Dis. 2017;17(1):39-49. DOI: 10.1016/S1473-3099(16)30274-2

2017
Journal Article

Hiza H, Doulla B, Sasamalo M, Hella J, Kamwela L, Mhimbira F, Reither K, Gagneux S, Jugheli L, Fenner L. Preservation of sputum samples with cetylpyridinium chloride (CPC) for tuberculosis cultures and Xpert MTB/RIF in a low-income country. BMC Infect Dis. 2017;17:542. DOI: 10.1186/s12879-017-2642-z

2017
Journal Article
PubMed (28778186)
Link

Mhimbira F, Hella J, Said K, Kamwela L, Sasamalo M, Maroa T, Chiryamkubi M, Mhalu G, Schindler C, Reither K, Knopp S, Utzinger J, Gagneux S, Fenner L. Prevalence and clinical relevance of helminth co-infections among tuberculosis patients in urban Tanzania. PLoS Negl Trop Dis. 2017;11(2):e0005342. DOI: 10.1371/journal.pntd.0005342

2017
Journal Article
PubMed (28178325)
Link

Reither K. Improving the diagnostics of tuberculosis - clinical evaluation of four new diagnostics. Basel: Univ. Basel, 2017. PhD Thesis, University of Basel, Faculty of Science

2017
Thesis
Link

Said K, Verver S, Kalingonji A, Lwilla F, Mkopi A, Charalambous S, Reither K. Tuberculosis among HIV-infected population: incidence and risk factors in rural Tanzania. Afr Health Sci. 2017;17(1):208-215

2017
Journal Article
PubMed (9251592)

Bholla M, Kapalatad N, Masikad E, Chandee H, Jughelia L, Sasamaloc M, Glass T.R, Beck H.P, Reither K. Evaluation of Xpert® MTB/RIF and Ustar EasyNATTM TB IAD for diagnosis of TB lymphadenitis of children in Tanzania. BMC Infect Dis. 2016;16:246. DOI: 10.1186/s12879-016-1578-z

2016
Journal Article
PubMed (27268404)
Link

Boillat-Blanco N, Bovet P, Ramaiya K.L, Mganga M, Minja L.T, Saleh L, Imboden M, Schindler C, Gagneux S, Daubenberger C, Reither K, Probst-Hensch N. Association between tuberculosis, diabetes and 25 hydroxyvitamin D in Tanzania: a longitudinal case control study. BMC Infect Dis. 2016;16:626. DOI: 10.1186/s12879-016-1960-x

2016
Journal Article
PubMed (27809789)
Link

Boillat-Blanco N, Ramaiya K.L, Mganga M, Minja L.T, Bovet P, Schindler C, Von Eckardstein A, Gagneux S, Daubenberger C, Reither K, Probst-Hensch N. Transient hyperglycemia in patients with tuberculosis in Tanzania: implications for diabetes screening algorithms. J Infect Dis. 2016;213(7):1163-1172. DOI: 10.1093/infdis/jiv568

2016
Journal Article
PubMed (26609005)

Mhimbira F, Hella J, Maroa T, Kisandu S, Chiryamkubi M, Said K, Mhalu G, Mkopi A, Mutayoba B, Reither K, Gagneux S, Fenner L. Home-based and facility-based directly observed therapy of tuberculosis treatment under programmatic conditions in urban Tanzania. PLoS One. 2016;11(8):e0161171. DOI: 10.1371/journal.pone.0161171

2016
Journal Article
PubMed (27513331)
Link

Petrone L, Cannas A, Vanini V, Cuzzi G, Aloi F, Nsubuga M, Sserunkuma J, Nazziwa R.A, Jugheli L, Lukindo T, Girardi E, Antinori A, Pucci L, Reither K, Goletti D. Blood and urine inducible protein 10 as potential markers of disease activity. Int J Tuberc Lung Dis. 2016;20(11):1554-1561. DOI: 10.5588/ijtld.16.0342

2016
Journal Article
PubMed (27776600)

Reither K. Aufbau von Kapizitäten für klinische Tuberkulosesstudien: das Schweiz-Tansania Modell. In: Reither K, ed. Deutsches Zentralkomitee zur Bekämpfung der Tuberkulose: 39. Informationsbericht, 26-31. Berlin: DZK, 2016

2016
Book Section

Sikalengo G, Ramirez A, Faini D, Mwamelo K, Battegay M, Jugheli L, Hatz C, Reither K, Letang E. Tuberculous spondylitis diagnosed through Xpert MTB/RIF assay in urine: a case report. BMC Infect Dis. 2016;16(1):514. DOI: 10.1186/s12879-016-1844-0

2016
Journal Article
PubMed (27670679)
Link

Zumla A, Rao M, Wallis R.S, Kaufmann S.H, Rustomjee R, Mwaba P, Vilaplana C, Yeboah-Manu D, Chakaya J, Ippolito G, Azhar E, Hoelscher M, Maeurer M, Host-Directed Therapies Network consortium. Host-directed therapies for infectious diseases: current status, recent progress, and future prospects. Lancet Infect Dis. 2016;16(4):e47-63. DOI: 10.1016/S1473-3099(16)00078-5

2016
Journal Article
PubMed (27036359)

Boillat-Blanco N, Mganga M, Ramaiya K.L, Mrangu N.S, Minja L.T, Schindler C, Von Eckardstein A, Gagneux S, Daubenberger C, Reither K, Probst-Hensch N. Longitudinal evolution of diabetes during tuberculosis in Dar es Salaam, Tanzania. Trop Med Int Health, 2015;20(Suppl. 1):57-58. Abstracts of the 9th European Congress on Tropical Medicine and International Health, 6-10 September 2015, Basel, Switzerland

2015
Conference Paper

Cabibbe A.M, Miotto P, Moure R, Alcaide F, Feuerriegel S, Pozzi G, Nikolayevskyy V, Drobniewski F, Niemann S, Reither K, Cirillo D.M. Lab-on-chip based platform for fast molecular diagnosis of multi-drug resistant tuberculosis. J Clin Microbiol. 2015;53(12):3876-3880. DOI: 10.1128/JCM.01824-15

2015
Journal Article
PubMed (26246486)

Dawson R, Diacon A.H, Everitt D, Van Niekerk C, Donald P.R, Burger D.A, Schall R, Spigelman M, Conradie A, Eisenach K, Venter A, Ive P, Page-Shipp L, Variava K, Reither K, Ntinginya E.N, Pym A, Von Groote-Bindlingmaier F, Mendel C.M. Efficiency and safety of the combination of moxifloxacin, pretomanid (PA-824), and pyrazinamide during the first 8 weeks of antituberculosis treatment: a phase 2b, open-label, partly randomised trial in patients with drug-susceptible or drug-resistant pul. Lancet. 2015;385(9979):1738-1747. DOI: 10.1016/S0140-6736(14)62002-X

2015
Journal Article
PubMed (25795076)

Heinrich N, Dawson R, du Bois J, Narunsky K, Horwith G, Phipps A.J, Nacy C.A, Aarnoutse R.E, Boeree M.J, Gillespie S.H, Venter A, Henne S, Rachow A, Phillips P.P, Hoelscher M, Diacon A.H, Pan African Consortium for the Evaluation of Antituberculosis Antibiotics (PanACEA). Early phase evaluation of SQ109 alone and in combination with rifampicin in pulmonary TB patients. J Antimicrob Chemother. 2015;70(5):1558-1566. DOI: 10.1093/jac/dku553

2015
Journal Article
PubMed (25630641)

Kroidl I, Clowes P, Reither K, Mtafya B, Rojas-Ponce G, Ntinginya E.N, Kalomo M, Minja L.T, Kowuor D, Saathoff E, Kroidl A, Heinrich N, Maboko L, Bates M, O'Grady J, Zumla A, Hoelscher M, Rachow A. Performance of urine lipoarabinomannan assays for paediatric tuberculosis in Tanzania. Eur Respir J. 2015;46(3):761-770. DOI: 10.1183/09031936.00003315

2015
Journal Article
PubMed (26113682)

Kroidl I, Podola L, Clowes P, Rachow A, Reither K, Saathoff E, Geldmacher C, Kalomo M, Ntinginya E.N, Maboko L, Kroidl A, Loescher T, Hoelscher M. Diagnostic value of three interferon-gamma release assays for paediatric tuberculosis in a high HIV/TB -prevalence setting in south-west Tanzania. Trop Med Int Health, 2015;20(Suppl. 1):151. Abstracts of the 9th European Congress on Tropical Medicine and International Health, 6-10 September 2015, Basel, Switzerland

2015
Conference Paper

Lenz N, Schindler T, Kagina B.M, Zhang J.D, Lukindo T, Mpina M, Bang P, Kromann I, Hoff S.T, Andersen P, Reither K, Churchyard G.J, Certa U, Daubenberger C.A. Antiviral innate immune activation in HIV infected adults negatively affects H1/IC31(R) induced vaccine-specific memory CD4+ T cells. Clin Vaccine Immunol. 2015;22(7):688-696. DOI: 10.1128/CVI.00092-15

2015
Journal Article
PubMed (25924764)