Publications

Bresser M, Erhardt R.M, Shanaube K, Simwinga M, Mahlatsi P.A, Belus J, Schaap A, Amstutz A, Gachie T, Glass T.R, Kangololo B, Mota J, Floyd S, Katende B, Klinkenberg E, Ayles H, Reither K, Ruperez M. Evaluation of COVID-19 antigen rapid diagnostic tests for self-testing in Lesotho and Zambia. PLoS One. 2024;19(2):e0280105. DOI: 10.1371/journal.pone.0280105

Gerber F, Semphere R, Lukau B, Mahlatsi P, Mtenga T, Lee T, Kohler M, Glass T.R, Amstutz A, Molatelle M, MacPherson P, Marake N.B, Nliwasa M, Ayakaka I, Burke R, Labhardt N. Same-day versus rapid ART initiation in HIV-positive individuals presenting with symptoms of tuberculosis: protocol for an open-label randomized non-inferiority trial in Lesotho and Malawi. PLoS One. 2024;19(2):e0288944. DOI: 10.1371/journal.pone.0288944

Vanobberghen F, Keter A.K, Jacobs B.K.M, Glass T.R, Lynen L, Law I, Murphy K, van Ginneken B, Ayakaka I, van Heerden A, Maama L, Reither K. Computer-aided detection thresholds for digital chest radiography interpretation in tuberculosis diagnostic algorithms. ERJ Open Res. 2024;10. DOI: 10.1183/23120541.00508-2023

Brown J.A, Nsakala B.L, Mokhele K, Rakuoane I, Muhairwe J, Glass T.R, Amstutz A, Tschumi N, Belus J.M, Klimkait T, Labhardt N.D. Dolutegravir in real life: self-reported mental and physical health outcomes after transitioning from efavirenz- to dolutegravir-based antiretroviral therapy in a prospective cohort study in Lesotho. HIV Med. 2023;24(2):153-162. DOI: 10.1111/hiv.13352

Castillo-Mancilla J.R, Morrow M, Hunt P.W, Schnittman S.R, Phillips A.N, Baker J.V, Haberer J.E, Janeiro M.J, Aragao F, Cohen C, Musinguzi N, Brown T.T, Cavassini M, Glass T.R, Serrano-Villar S, Mawhinney S, Siedner M. Beyond undetectable: modeling the clinical benefit of improved antiretroviral adherence in persons with human immunodeficiency virus with virologic suppression. Open Forum Infect Dis. 2023;10(5):ofad230. DOI: 10.1093/ofid/ofad230

Kalinjuma A.V, Glass T.R, Masanja H, Weisser M, Msengwa A.S, Vanobberghen F, Otwombe K. Statistical methods applied for the assessment of the HIV cascade and continuum of care: a systematic scoping review. BMJ Open. 2023;13(11):e071392. DOI: 10.1136/bmjopen-2022-071392

Kalinjuma A.V, Hussey H, Mollel G.J, Letang E, Battegay M, Glass T.R, Paris D, Vanobberghen F, Weisser M, KIULARCO study group. Body mass index trends and its impact of under and overweight on outcome among PLHIV on antiretroviral treatment in rural Tanzania: a prospective cohort study. PLoS One. 2023;18(8):e0290445. DOI: 10.1371/journal.pone.0290445

Katende B, Bresser M, Kamele M, Chere L, Tlahali M, Erhardt R.M, Muhairwe J, Ayakaka I, Glass T.R, Ruhwald M, van Ginneken B, Murphy K, de Vos M, Amstutz A, Mareka M, Mooko S.M, Reither K, González Fernández L. Impact of a multi-disease integrated screening and diagnostic model for COVID-19, TB, and HIV in Lesotho. PLOS Glob Public Health. 2023;3(8):e0001488. DOI: 10.1371/journal.pgph.0001488

Kopo M, Lejone T.I, Tschumi N, Glass T.R, Kao M, Brown J.A, Seiler O, Muhairwe J, Moletsane N, Labhardt N.D, Amstutz A. Effectiveness of a peer educator-coordinated preference-based differentiated service delivery model on viral suppression among young people living with HIV in Lesotho: the PEBRA cluster-randomized trial. PLoS Med. 2023;20(1):e1004150. DOI: 10.1371/journal.pmed.1004150

Labhardt N.D, González Fernández L, Katende B, Muhairwe J, Bresser M, Amstutz A, Glass T.R, Ruhwald M, Sacks J.A, Escadafal C, Mareka M, Mooko S.M, de Vos M, Reither K. Head-to-head comparison of nasal and nasopharyngeal sampling using SARS-CoV-2 rapid antigen testing in Lesotho. PLoS One. 2023;18(3):e0278653. DOI: 10.1371/journal.pone.0278653

Mnzava D, Okuma J, Ndege R, Kimera N, Ntamatungiro A, Nyuri A, Byakuzana T, Abilahi F, Mayeka P, Temba E, Fanuel T, Glass T.R, Klimkait T, Vanobberghen F, Weisser M, KIULARCO Study Group. Decentralization of viral load testing to improve HIV care and treatment cascade in rural Tanzania: observational study from the Kilombero and Ulanga Antiretroviral Cohort. BMC Infect Dis. 2023;23:222. DOI: 10.1186/s12879-023-08155-6

Murphy K, Muhairwe J, Schalekamp S, van Ginneken B, Ayakaka I, Mashaete K, Katende B, van Heerden A, Bosman S, Madonsela T, González Fernández L, Signorell A, Bresser M, Reither K, Glass T.R. COVID-19 screening in low resource settings using artificial intelligence for chest radiographs and point-of-care blood tests. Sci Rep. 2023;13:19692. DOI: 10.1038/s41598-023-46461-w

Seiler O, Kopo M, Kao M, Lejone T.I, Tschumi N, Glass T.R, Brown J.A, Labhardt N.D, Amstutz A. HIV care preferences among young people living with HIV in Lesotho: a secondary data analysis of the PEBRA cluster randomized trial. AIDS Res Treat. 2023;2023:8124192. DOI: 10.1155/2023/8124192

Haak F, Kollmar O, Ioannidis A, Slotta J.E, Ghadimi M.B, Glass T, von Strauss und Torney M. Predicting complicated appendicitis based on clinical findings: the role of Alvarado and appendicitis inflammatory response scores. Langenbecks Arch Surg. 2022;407(5):2051-2057. DOI: 10.1007/s00423-022-02533-5

Haak F, Poletti T, Grossman N, von Holzen U, Bolli M, Klasen J.M, Glass T, von Strauss M, Torney M.D. Interprofessional differences in preoperative planning: the individualist surgeon. European Surgery. 2022;54(5):267-272. DOI: 10.1007/s10353-022-00761-z

Katende B, González Fernández L, Muhairwe J, Glass T.R, Ayakaka I, Labhardt N.D, Ruhwald M, de Vos M, Bresser M, Reither K. Diagnosis of SARS-CoV-2 infection from breath: a proof-of-concept study. IJID Reg. 2022;5:163-164. DOI: 10.1016/j.ijregi.2022.10.007

Magnolini R, Senkoro E, Kalinjuma A.V, Kitau O, Kivuma B, Samson L, Eichenberger A, Mollel G.J, Krinke E, Okuma J, Ndege R, Glass T, Mapesi H, Vanobberghen F, Battegay M, Weisser M. Stigma-directed services (Stig2Health) to improve 'linkage to care' for people living with HIV in rural Tanzania: study protocol for a nested pre-post implementation study within the Kilombero and Ulanga Antiretroviral Cohort. AAS Open Res. 2022;5:14. DOI: 10.12688/aasopenres.13353.2

Mollel G.J, Moshi L, Hazem H, Eichenberger A, Kitau O, Mapesi H, Glass T.R, Paris D.H, Weisser M, Vanobberghen F. Causes of death and associated factors over a decade of follow-up in a cohort of people living with HIV in rural Tanzania. BMC Infect Dis. 2022;22:37. DOI: 10.1186/s12879-021-06962-3

Muhairwe J.A, Brown J.A, Motaboli L, Nsakala B.L, Lerotholi M, Amstutz A, Klimkait T, Glass T.R, Labhardt N.D. The suboptimal pediatric HIV viral load cascade: multidistrict cohort study among children taking antiretroviral therapy in Lesotho, Southern Africa. Pediatr Infect Dis J. 2022;41(3):e75-e80. DOI: 10.1097/INF.0000000000003415

Ndege R.C, Okuma J, Kalinjuma A.V, Mkumbo J, Senkoro E, Fue G, Samson L, Mapesi H, Shabani S, Glass T.R, Battegay M, Paris D.H, Vanobberghen F, Weisser M, KIULARCO Study Group. Failure to return pillbox is a predictor of being lost to follow-up among people living with HIV on antiretroviral therapy in rural Tanzania. HIV Med. 2022;23(6):661-672. DOI: 10.1111/hiv.13223

Willburger J.C.F, von Strauss M, Peterson C.J, Glass T.R, Kettelhack C. Incidence, treatment and outcome of patients with retroperitoneal soft-tissue sarcoma in Switzerland 2005-2015: a population-based analysis. World J Surg. 2022;46(2):461-468. DOI: 10.1007/s00268-021-06374-z

Amstutz A, Lejone T.I, Khesa L, Kopo M, Kao M, Muhairwe J, Bresser M, Räber F, Klimkait T, Battegay M, Glass T.R, Labhardt N.D. Offering ART refill through community health workers versus clinic-based follow-up after home-based same-day ART initiation in rural Lesotho: the VIBRA cluster-randomized clinical trial. PLoS Med. 2021;18(10):e1003839. DOI: 10.1371/journal.pmed.1003839

Amstutz A, Matsela L, Lejone T.I, Kopo M, Glass T.R, Labhardt N.D. Reaching absent and refusing individuals during home-based HIV testing through self-testing-at what cost?. Front Med. 2021;8:653677. DOI: 10.3389/fmed.2021.653677

Castillo-Mancilla J.R, Cavassini M, Schneider M.P, Furrer H, Calmy A, Battegay M, Scanferla G, Bernasconi E, Gunthard H.F, Glass T.R, Swiss HIV Cohort Study. Association of incomplete adherence to antiretroviral therapy with cardiovascular events and mortality in virologically suppressed persons with HIV: the Swiss HIV cohort study. Open Forum Infect Dis. 2021;8(2):ofab032. DOI: 10.1093/ofid/ofab032

Glass T.R, Günthard H, Calmy A, Bernasconi E, Scherrer A.U, Battegay M, Steffen A, Böni J, Yerly S, Klimkait T, Cavassini M, Furrer H, Swiss HIV Cohort Study. The role of HIV asymptomatic status when starting ART on adherence and treatment outcomes and implications for test and treat: the Swiss HIV Cohort Study. Clin Infect Dis. 2021;72(8):1413-1421. DOI: 10.1093/cid/ciaa239

Kümmerle A, Sikalengo G, Vanobberghen F, Ndege R.C, Foe G, Schlaeppi C, Burri C, Battegay M, Paris D.H, Glass T.R, Weisser M, Marzolini C, Kiularco Study Group. Recognition and management of clinically significant drug-drug interactions between antiretrovirals and co-medications in a cohort of people living with HIV in rural Tanzania: a prospective questionnaire-based study. J Antimicrob Chemother. 2021;76(10):2681-2689. DOI: 10.1093/jac/dkab254

Mapesi H, Gupta R, Wilson H.I, Lukau B, Amstutz A, Lyimo A, Muhairwe J, Senkoro E, Byakuzana T, Mphunyane M, Bresser M, Glass T.R, Lambiris M, Fink G, Gingo W, Battegay M, Paris D.H, Rohacek M, Vanobberghen F, Labhardt N.D, Burkard T, Weisser M. The coArtHA trial—identifying the most effective treatment strategies to control arterial hypertension in sub-Saharan Africa: study protocol for a randomized controlled trial. Trials. 2021;22:77. DOI: 10.1186/s13063-021-05023-z

Mapesi H, Okuma J, Franzeck F, Wilson H.I, Senkoro E, Byakuzana T, Ndege R, Vanobberghen F, Glass T.R, Battegay M, Weisser M, Paris D.H, KIULARCO Study Group. Prevalence, incidence and predictors of renal impairment in persons with HIV receiving protease-inhibitors in rural Tanzania. PLoS One. 2021;16(12):e0261367. DOI: 10.1371/journal.pone.0261367

Multerer L, Glass T.R, Vanobberghen F, Smith T. Analysis of contamination in cluster randomized trials of malaria interventions. Trials. 2021;22:613. DOI: 10.1186/s13063-021-05543-8

Multerer L, Vanobberghen F, Glass T.R, Hiscox A, Lindsay S.W, Takken W, Tiono A, Smith T. Estimating intervention effectiveness in trials of malaria interventions with contamination. Malar J. 2021;20:413. DOI: 10.1186/s12936-021-03924-7

Ramser M, Glauser P.M, Glass T.R, Weixler B, Grapow M.T.R, Hoffmann H, Kirchhoff P. Abdominal decompression after cardiac surgery: outcome of 42 patients with abdominal compartment syndrome. World J Surg. 2021;45(4):1242-1251. DOI: 10.1007/s00268-020-05917-0

Vanobberghen F, Lweno O, Kümmerle A, Mwebi K.D, Asilia P, Simon B, Mswata S, Schmidlin S, Glass T.R, Daubenberger C, Tanner M, Meyer-Monard S. Efficacy and safety of intravenous ferric carboxymaltose compared with oral iron for the treatment of iron deficiency anaemia in women after childbirth in Tanzania: a parallelgroup, open-label, randomised controlled phase 3 trial. Lancet Glob Health. 2021;9(2):e189-e198. DOI: 10.1016/S2214-109X(20)30448-4

Vanobberghen F, Weisser M, Kasuga B, Katende A, Battegay M, Tanner M, Glass T.R, KIULARCO Study Group. Mortality in a cohort of people living with HIV in rural Tanzania, accounting for unseen mortality among those lost to follow-up. Am J Epidemiol. 2021;190(2):251-264. DOI: 10.1093/aje/kwaa176

Amstutz A, Brown J.A, Ringera I, Muhairwe J, Lejone T.I, Klimkait T, Glass T.R, Labhardt N.D. Engagement in care, viral suppression, drug resistance and reasons for non-engagement after home-based same-day ART initiation in Lesotho: a two-year follow-up of the CASCADE trial. Clin Infect Dis. 2020;71(10):2608-2614. DOI: 10.1093/cid/ciz1126

Amstutz A, Kopo M, Lejone T.I, Khesa L, Kao M, Muhairwe J, Glass T.R, Labhardt N.D. "If it is left, it becomes easy for me to get tested": use of oral self-tests and community health workers to maximize the potential of home-based HIV testing among adolescents in Lesotho. J Int AIDS Soc. 2020;23(Suppl. 5):e25563. DOI: 10.1002/jia2.25563

Amstutz A, Lejone T.I, Khesa L, Muhairwe J, Bresser M, Vanobberghen F, Kopo M, Kao M, Nsakala B.L, Tlali K, Klimkait T, Battegay M, Labhardt N.D, Glass T.R. Home-based oral self-testing for absent and declining individuals during a door-to-door HIV testing campaign in rural Lesotho (HOSENG): a cluster-randomised trial. Lancet HIV. 2020;7(11):e752-e761. DOI: 10.1016/S2352-3018(20)30233-2

Amstutz A, Nsakala B.L, Vanobberghen F, Muhairwe J, Glass T.R, Namane T, Mpholo T, Battegay M, Klimkait T, Labhardt N.D. Switch to second-line versus continued first-line antiretroviral therapy for patients with low-level HIV-1 viremia: an open-label randomized controlled trial in Lesotho. PLoS Med. 2020;17(9):e1003325. DOI: 10.1371/journal.pmed.1003325

Arpagaus A, Franzeck F.C, Sikalengo G, Ndege R, Mnzava D, Rohacek M, Hella J, Reither K, Battegay M, Glass T.R, Paris D.H, Bani F, Rajab O.N, Weisser M, Kiularco Study Group. Extrapulmonary tuberculosis in HIV-infected patients in rural Tanzania: the prospective Kilombero and Ulanga antiretroviral cohort. PLoS One. 2020;15(3):e0229875. DOI: 10.1371/journal.pone.0229875

Bircher R.E, Ntamatungiro A.J, Glass T.R, Mnzava D, Nyuri A, Mapesi H, Paris D.H, Battegay M, Klimkait T, Weisser M, Kiularco Study Group. High failure rates of protease inhibitor-based antiretroviral treatment in rural Tanzania - a prospective cohort study. PLoS One. 2020;15(1):e0227600. DOI: 10.1371/journal.pone.0227600

Brown J.A, Ringera I, Luoga E, Cheleboi M, Kimera N, Muhairwe J, Kayembe B.P, Molapo Hlasoa M, Kabundi L, Yav C.W.D, Mothobi B, Thahane L, Amstutz A, Bachmann N, Mollel G.J, Bresser M, Glass T.R, Paris D.H, Klimkait T, Weisser M, Labhardt N.D. Genotype-Informed Versus Empiric Management Of VirEmia (GIVE MOVE): study protocol of an open-label randomised clinical trial in children and adolescents living with HIV in Lesotho and Tanzania. BMC Infect Dis. 2020;20:773. DOI: 10.1186/s12879-020-05491-9