Heat-related cardiovascular morbidity and mortality in Switzerland: a clinical perspective (Publications)
AIMS: Previous studies found increased cardiovascular mortality during hot days, while emergency hospital admissions were decreasing. We explored potential underlying reasons by analysing clinically s
The sputum microbiome in pulmonary tuberculosis and its association with disease manifestations: a cross-sectional study (Publications)
Each day, approximately 27,000 people become ill with tuberculosis (TB), and 4,000 die from this disease. Pulmonary TB is the main clinical form of TB, and affects the lungs with a considerably hetero
Novel tools and strategies for breaking schistosomiasis transmission: study protocol for an intervention study (Publications)
BACKGROUND: Global elimination of schistosomiasis as a public health problem is set as target in the new World Health Organization's Neglected Tropical Diseases Roadmap for 2030. Due to a long history
Urban-rural gaps in breastfeeding practices: evidence from Lao People's Democratic Republic (Publications)
Objectives: Breastfeeding rates are decreasing rapidly in many low and middle-income countries, disproportionately affecting urban residences. We use data from Lao People's Democratic Republic to iden
The role of children and adolescents in the SARS-CoV-2 pandemic: a rapid review (Publications)
BACKGROUND: There has been much discussion about coronavirus disease 2019 (COVID-19) and the virus that causes it, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in children and adolesce
From magic bullet to magic bomb: reductive bioactivation of antiparasitic agents (Publications)
Paul Ehrlich coined the term "magic bullet" to describe how a drug kills the parasite inside its human host without harming the host itself. Ehrlich concluded that the drug must have a greater affinit
A household-based community health worker programme for non-communicable disease, malnutrition, tuberculosis, HIV and maternal health: a stepped-wedge... (Publications)
BACKGROUND: Community health worker (CHW) programmes are a valuable component of primary care in resource-poor settings. The evidence supporting their effectiveness generally shows improvements in dis
Design of proteasome inhibitors with oral efficacy <em>in vivo</em> against<em> Plasmodium falciparum</em> and selectivity over the human proteasome (Publications)
The Plasmodium falciparum proteasome is a potential antimalarial drug target. We have identified a series of amino-amide boronates that are potent and specific inhibitors of the P. falciparum 20S prot