Limited antigenic diversity of <em>Plasmodium falciparum</em> apical membrane antigen 1 supports the development of effective multi-allele vaccines (Publications)
BackgroundPolymorphism in antigens is a common mechanism for immune evasion used by many important pathogens, and presents major challenges in vaccine development. In malaria, many key immune targets
Identification of the <em>Mycobacterium ulcerans</em> protein MUL_3720 as a promising target for the development of a diagnostic test for Buruli ulcer (Publications)
Buruli ulcer (BU) caused by Mycobacterium ulcerans is a devastating skin disease, occurring mainly in remote West African communities with poor access to health care. Early case detection and subseque
Estimating the global burden of endemic canine rabies (Publications)
BACKGROUND: Rabies is a notoriously underreported and neglected disease of low-income countries. This study aims to estimate the public health and economic burden of rabies circulating in domestic dog
Simple fecal flotation is a superior alternative to guadruple kato katz smear examination for the detection of hookworm eggs in human stool (Publications)
BACKGROUND: Microscopy-based identification of eggs in stool offers simple, reliable and economical options for assessing the prevalence and intensity of hookworm infections, and for monitoring the su
Evaluating preservation methods for identifying <em>Anopheles gambiae s.s.</em> and <em>Anopheles arabiensis</em> complex mosquitoes species using... (Publications)
BackgroundNear-infrared spectroscopy (NIRS) has been successfully used on fresh and RNAlater(R)-preserved members of the Anopheles gambiae complex to identify sibling species and age. No preservation
The roles of water, sanitation and hygiene in reducing schistosomiasis: a review (Publications)
Schistosomiasis is a disease caused by infection with blood flukes of the genus Schistosoma. Transmission of, and exposure to, the parasite result from faecal or urinary contamination of freshwater co