Heterogeneous distribution of <em>Plasmodium falciparum</em> drug resistance haplotypes in subsets of the host population (Publications)
BACKGROUND: The emergence of drug resistance is a major problem in malaria control. For mathematical modelling of the transmission and spread of drug resistance the determinant parameters need to be i
Social and cultural features of cholera and shigellosis in peri-urban and rural communities of Zanzibar (Publications)
ABSTRACT: BACKGROUND: Responding to the high burden of cholera in developing countries, the WHO now considers vaccination as a supplement to the provision of safe drinking water and improved sanitatio
Habitat characterization and spatial distribution of <em>Anopheles </em>sp. mosquito larvae in Dar es Salaam (Tanzania) during an extended dry period (Publications)
INTRODUCTION: By 2030, more than 50% of the African population will live in urban areas. Controlling malaria reduces the disease burden and further improves economic development. As a complement to tr
Studies on the mechanisms supporting the continuous growth of <em>Trypanosoma (Trypanozoon) brucei</em> as bloodstream-like form in vitro (Publications)
The conditions which enable growth of Trypanosoma (T.) brucei stock S 427 as bloodstream-like form over bovine fibroblast-like cells (BHF) were analyzed. The experiments with different BHF conditioned
FlexiChip package: an universal microarray with a dedicated analysis software for high-thoughput SNPs detection linked to anti-malarial drug... (Publications)
BACKGROUND: A number of molecular tools have been developed to monitor the emergence and spread of anti-malarial drug resistance to Plasmodium falciparum. One of the major obstacles to the wider imple
Development of highly organized lymphoid structures in Buruli ulcer lesions after treatment with rifampicin and streptomycin (Publications)
BACKGROUND: Buruli ulcer caused by Mycobacterium ulcerans is an infection of the subcutaneous tissue leading to chronic necrotising skin ulcers. The pathogenesis is associated with the cytocidal and i