Beyond immune escape: a variant surface glycoprotein causes suramin resistance in <em>Trypanosoma brucei</em> (Publications)
Suramin is one of the first drugs developed in a medicinal chemistry program (Bayer, 1916), and it is still the treatment of choice for the hemolymphatic stage of African sleeping sickness caused by T
Estimating the burden of scrub typhus: a systematic review (Publications)
BACKGROUND: Scrub typhus is a vector-borne zoonotic disease that can be life-threatening. There are no licensed vaccines, or vector control efforts in place. Despite increasing awareness in endemic re
First detection of N1575Y mutation in pyrethroid resistant <em>Anopheles gambiae</em> in Southern Côte d'Ivoire (Publications)
Background. The intensification of insecticide use for both public health and agriculture in Africa has contributed to growing insecticide resistance. Today, resistance to World Health Organization (W
Informing new or improved vector control tools for reducing the malaria burden in Tanzania: a qualitative exploration of perceptions of mosquitoes and... (Publications)
BACKGROUND: The effectiveness of malaria prevention with long-lasting insecticidal nets and indoor residual spraying is limited by emerging insecticide resistance, evasive mosquito behaviours that inc
Software application profile: opal and mica: open-source software solutions for epidemiological data management, harmonization and dissemination (Publications)
Motivation: Improving the dissemination of information on existing epidemiological studies and facilitating the interoperability of study databases are essential to maximizing the use of resources and
Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195... (Publications)
BACKGROUND: Measurement of changes in health across locations is useful to compare and contrast changing epidemiological patterns against health system performance and identify specific needs for reso
Exposure to elemental composition of outdoor PM2.5 at birth and cognitive and psychomotor function in childhood in four European birth cohorts (Publications)
BACKGROUND: Little is known about developmental neurotoxicity of particulate matter composition. We aimed to investigate associations between exposure to elemental composition of outdoor PM2.5 at birt
Fine-scale spatial and temporal heterogeneities in insecticide resistance profiles of the malaria vector,<em> Anopheles arabiensis</em> in rural... (Publications)
Background: Programmatic monitoring of insecticide resistance in disease vectors is mostly done on a large scale, often focusing on differences between districts, regions or countries. However, local