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1. Assembling a global database of child pneumonia studies to inform WHO pneumonia management algorithm: methodology and applications (Publications)

   Assembling a global database of child pneumonia studies to inform WHO pneumonia management algorithm: methodology and applications

   Relevance:

   BACKGROUND: The existing World Health Organization (WHO) pneumonia case management guidelines rely on clinical symptoms and signs for identifying, classifying, and treating pneumonia in children up to

2. Comparison of model predictions of typhoid conjugate vaccine public health impact and cost-effectiveness (Publications)

   Comparison of model predictions of typhoid conjugate vaccine public health impact and cost-effectiveness

   Relevance:

   Models are useful to inform policy decisions on typhoid conjugate vaccine (TCV) deployment in endemic settings. However, methodological choices can influence model-predicted outcomes. To provide robus

3. Household-level risk factors for water contamination and antimicrobial resistance in drinking water among households with children under 5 in rural... (Publications)

   Household-level risk factors for water contamination and antimicrobial resistance in drinking water among households with children under 5 in rural San Marcos, Cajamarca, Peru

   Relevance:

   Household water contamination at point of use depends on human, animal and environmental factors embodying all aspects of a One Health approach. This study investigated the association between househo

4. Limited efficacy of repeated praziquantel treatment in <em>Schistosoma mansoni</em> infections as revealed by highly accurate diagnostics, PCR and... (Publications)

   Limited efficacy of repeated praziquantel treatment in <em>Schistosoma mansoni</em> infections as revealed by highly accurate diagnostics, PCR and UCP-LF CAA (RePST trial)

   Relevance:

   BACKGROUND: Most studies assessing praziquantel (PZQ) efficacy have used relatively insensitive diagnostic methods, thereby overestimating cure rate (CR) and intensity reduction rate (IRR). To determi

5. Ambient prenatal air pollution exposure is associated with low cord blood IL-17a in infants (Publications)

   Ambient prenatal air pollution exposure is associated with low cord blood IL-17a in infants

   Relevance:

6. Helminth infections: enabling the World Health Organization road map (Publications)

   Helminth infections: enabling the World Health Organization road map

   Relevance:

   Helminthiases are considered among the most persistent public health problems. Control and/or elimination remains a global health challenge and the World Health Organization Road Map highlights critic

7. Advancing detection and response capacities for emerging and re-emerging pathogens in Africa (Publications)

   Advancing detection and response capacities for emerging and re-emerging pathogens in Africa

   Relevance:

   Recurrent disease outbreaks caused by a range of emerging and resurging pathogens over the past decade reveal major gaps in public health preparedness, detection, and response systems in Africa. Under

8. Pre-referral rectal artesunate: no cure for unhealthy systems (Publications)

   Pre-referral rectal artesunate: no cure for unhealthy systems

   Relevance:

   Pre-referral rectal artesunate suppositories can save the lives of children with severe malaria if patients receive adequate post-referral care. A multi-country randomised controlled trial reporting o

9. Evaluation of nanopore sequencing for <em>Mycobacterium tuberculosis </em>drug susceptibility testing and outbreak investigation: a genomic analysis (Publications)

   Evaluation of nanopore sequencing for <em>Mycobacterium tuberculosis </em>drug susceptibility testing and outbreak investigation: a genomic analysis

   Relevance:

   BACKGROUND: Mycobacterium tuberculosis whole-genome sequencing (WGS) has been widely used for genotypic drug susceptibility testing (DST) and outbreak investigation. For both applications, Illumina te

10. Health system readiness and the implementation of rectal artesunate for severe malaria in sub-Saharan Africa: an analysis of real-world costs and... (Publications)

    Health system readiness and the implementation of rectal artesunate for severe malaria in sub-Saharan Africa: an analysis of real-world costs and constraints

    Relevance:

    BACKGROUND: Rectal artesunate, an efficacious pre-referral treatment for severe malaria in children, was deployed at scale in Uganda, Nigeria, and DR Congo. In addition to distributing rectal artesuna